Early chronic obstructive pulmonary disease: definition, assessment, and prevention

SI Rennard, MB Drummond - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. COPD, however, is a heterogeneous collection of diseases with differing causes …

[HTML][HTML] Muscle dysfunction in chronic obstructive pulmonary disease: update on causes and biological findings

J Gea, S Pascual, C Casadevall… - Journal of thoracic …, 2015 - ncbi.nlm.nih.gov
Respiratory and/or limb muscle dysfunction, which are frequently observed in chronic
obstructive pulmonary disease (COPD) patients, contribute to their disease prognosis …

Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled …

T Köhnlein, W Windisch, D Köhler, A Drabik… - The Lancet …, 2014 - thelancet.com
Background Evidence is weak for the ability of long-term non-invasive positive pressure
ventilation (NPPV) to improve survival in patients with stable hypercapnic chronic obstructive …

Respiratory and limb muscle dysfunction in COPD

E Barreiro, J Gea - COPD: Journal of Chronic Obstructive …, 2015 - Taylor & Francis
In the next decade, Chronic Obstructive Pulmonary Disease (COPD) will be a major leading
cause of death worldwide. Impaired muscle function and mass are common systemic …

The roles of miRNAs as potential biomarkers in lung diseases

SD Alipoor, IM Adcock, J Garssen, E Mortaz… - European journal of …, 2016 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs which can act as master regulators of
gene expression, modulate almost all biological process and are essential for maintaining …

Hypercapnia in COPD: causes, consequences, and therapy

B Csoma, MR Vulpi, S Dragonieri, A Bentley… - Journal of Clinical …, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder that
may lead to gas exchange abnormalities, including hypercapnia. Chronic hypercapnia is an …

Nutritional state and COPD: Effects on dyspnoea and exercise tolerance

A Tramontano, P Palange - Nutrients, 2023 - mdpi.com
Chronic Obstructive Pulmonary Disease (COPD) is a disease that is spreading worldwide
and is responsible for a huge number of deaths annually. It is characterized by progressive …

Respiratory disease and the oesophagus: reflux, reflexes and microaspiration

LA Houghton, AS Lee, H Badri, KR DeVault… - Nature reviews …, 2016 - nature.com
Gastro-oesophageal reflux is associated with a wide range of respiratory disorders,
including asthma, isolated chronic cough, idiopathic pulmonary fibrosis, chronic obstructive …

[HTML][HTML] Mechanisms, assessment and therapeutic implications of lung hyperinflation in COPD

A Rossi, Z Aisanov, S Avdeev, G Di Maria… - Respiratory …, 2015 - Elsevier
The main complaint of patients with chronic obstructive pulmonary disease (COPD) is
shortness of breath with exercise, that is usually progressive. The principal mechanism that …

Guidelines for the evaluation and treatment of muscle dysfunction in patients with chronic obstructive pulmonary disease

E Barreiro, V Bustamante, P Cejudo, JB Gáldiz… - Archivos de …, 2015 - Elsevier
In patients with chronic obstructive pulmonary disease (COPD), skeletal muscle dysfunction
is a major comorbidity that negatively impacts their exercise capacity and quality of life. In …