Methods: We performed an extensive literature search in Google Scholar and Pub Med
databases that were published between December 7, 1999 and January 9, 2018 in …

In the the past two decades the medical use of prescription opioids (POs), in particular
oxycodone, increased up to 14-fold in the US and Canada. The high consumption of these …

Objectives To assess whether declines in life expectancy occurred across high income
countries during 2014-16, to identify the causes of death contributing to these declines, and …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Background Opioid analgesics play a key role in pain management but providing access
while mitigating risk of misuse and dependence remains a challenge. Tracking global …

Background While data from USA and Canada demonstrate an opioid overdose epidemic,
very little nation‐wide European studies have been published on this topical subject …

Aim The aim of this paper is to investigate 25‐year trends in community use of prescribed
opioid analgesics in Australia, and to map these trends against major changes to opioid …

Chronic headache is particularly prevalent in migraineurs and it can progress to a condition
known as medication overuse headache (MOH). MOH is a secondary headache caused by …

Abstract In 2014, the American Society of Regional Anesthesia and Pain Medicine in
collaboration with the European Society of Regional Anaesthesia and Pain Therapy …

Importance The United States consumes most of the opioids worldwide despite representing
a small portion of the world's population. Dentists are one of the most frequent US …