Over two decades ago, increased levels of RNA oxidation were reported in postmortem
patients with ALS, Alzheimer's, Parkinson's, and other neurodegenerative diseases …

Abstract Background, Objectives Decrease in the revised ALS Functional Rating Scale
(ALSFRS-R) score is currently the most widely used measure of disease progression …

Amyotrophic lateral sclerosis (ALS) is a heterogeneous progressive neurodegenerative
disorder with available treatments such as riluzole and edaravone extending survival by an …

Objective To predict ALS progression with varying observation and prediction window
lengths, using machine learning (ML). Methods We used demographic, clinical, and …

Continuity of treatment in ALS: Benefits and challenges of maintaining riluzole over the course
of the disease - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (1).
This disease degenerates the upper and lower motor neurons of the brain motor cortex …

Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative
disease with a life-expectancy of only three to five years and few approved treatments. To …