Acetaminophen (APAP) is a commonly used analgesic drug that can cause liver injury, liver
necrosis and liver failure. APAP-induced liver injury is associated with glutathione depletion …

Context. Paracetamol (acetaminophen) ingestion is the most frequent pharmaceutical
overdose in the developed world. Metabolic acidosis sometimes occurs, but the acidosis is …

Objective To investigate the protective effects of Nigella sativa seed extract (NSSE) against
acetaminophen (APAP)-induced hepatotoxicity in TIB-73 cells and rats. Methods Toxicity in …

Fomepizole should be used more liberally in paracetamol overdose - Filip - 2023 - British Journal of
Clinical Pharmacology - Wiley Online Library Skip to Article Content Skip to Article Information …

Background Early, accurate prediction of survival is central to management of patients with
paracetamol-induced acute liver failure to identify those needing emergency liver …

This study is aimed at establishing the outcome of RSTI exposure to acetaminophen based
on a decision tree algorithm for the first time. This study used the National Poison Data …

Acetaminophen is one of the most commonly used analgesic drugs in the United States.
However, the outcomes of acute acetaminophen overdose might be very serious in some …

Context. Haemodialysis is sometimes used for patients with massive acetaminophen
overdose when signs of “mitochondrial paralysis”(lactic acidosis, altered mental status …

Poisoning remains a major cause of hospital admission into the emergency department and
intensive care unit. Proper diagnosis is the cornerstone for optimal management of poisoned …

Background Acetaminophen was first clinically used in 1955 and since then has become the
most commonly used antipyretic and analgesic medication in the United States …