The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …

Simple Summary Defects in a DNA repair pathway called mismatch repair (MMR) can lead
to cancer, including colorectal cancer (CRC). The detection of mismatch repair deficiency …

Abstract Background Immune-inflammatory biomarkers (IIBs) showed a prognostic
relevance in patients with metastatic CRC (mCRC). We aimed at evaluating the prognostic …

Background Curcumin is the main active ingredient of the spice turmeric, investigated
extensively for putative anticancer properties. Objectives This phase IIa open-labelled …

BACKGROUND Systemic inflammation and nutrition status play an important role in cancer
metastasis. The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP) …

Background The prognostic value of the systemic inflammatory response in cancer has been
well established in observational studies. This review aims to examine and rationalise the …

Introduction The systemic inflammatory response has been proven to have a prognostic
value. There are two methods of assessing the systemic inflammatory response composite …

Importance The role of primary tumor resection (PTR) in synchronous patients with
metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent …

The adiposity influence on colorectal cancer prognosis remains poorly characterised. We
performed a systematic review and meta‐analysis on post‐diagnosis adiposity measures …

Background Personalized therapy planning remains a significant challenge in advanced
colorectal cancer care, despite extensive research on prognostic and predictive markers. A …