Management of hepatocellular carcinoma: a review

ZJ Brown, DI Tsilimigras, SM Ruff, A Mohseni… - JAMA …, 2023 - jamanetwork.com
Importance Hepatocellular carcinoma (HCC) is the sixth most common malignancy and
fourth leading cause of cancer-related death worldwide. Recent advances in systemic and …

TKIs in combination with immunotherapy for hepatocellular carcinoma

B Stefanini, L Ielasi, R Chen, C Abbati… - Expert review of …, 2023 - Taylor & Francis
Introduction The treatment landscape of hepatocellular carcinoma (HCC) has significantly
changed over the last 5 years with multiple options in the frontline, second line, and beyond …

Efficacy and safety of nivolumab plus ipilimumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib: the CheckMate 040 …

T Yau, YK Kang, TY Kim, AB El-Khoueiry… - JAMA …, 2020 - jamanetwork.com
Importance Most patients with hepatocellular carcinoma (HCC) are diagnosed with
advanced disease not eligible for potentially curative therapies; therefore, new treatment …

Organoid models of human liver cancers derived from tumor needle biopsies

S Nuciforo, I Fofana, MS Matter, T Blumer, D Calabrese… - Cell reports, 2018 - cell.com
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the second
most frequent cause of cancer-related mortality worldwide. The multikinase inhibitor …

Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?

RR Ramjiawan, AW Griffioen, DG Duda - Angiogenesis, 2017 - Springer
Angiogenesis is defined as the formation of new blood vessels from preexisting vessels and
has been characterized as an essential process for tumor cell proliferation and viability. This …

A changing paradigm for the treatment of intermediate-stage hepatocellular carcinoma: Asia-Pacific primary liver cancer expert consensus statements

M Kudo, KH Han, SL Ye, J Zhou, YH Huang, SM Lin… - Liver cancer, 2020 - karger.com
Abstract The Asia-Pacific Primary Liver Cancer Expert (APPLE) Consensus Statement on
the treatment strategy for patients with intermediate-stage hepatocellular carcinoma (HCC) …

Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Antioxidants, 2022 - mdpi.com
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …

A new treatment option for intermediate-stage hepatocellular carcinoma with high tumor burden: initial lenvatinib therapy with subsequent selective TACE

M Kudo - Liver cancer, 2019 - karger.com
Transarterial chemoembolization (TACE) is the only guideline-recommended global
standard of care for intermediate-stage hepatocellular carcinoma (HCC). However, TACE is …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

Chinese expert consensus on multidisciplinary diagnosis and treatment of hepatocellular carcinoma with portal vein tumor thrombus (2018 Edition)

S Cheng, M Chen, J Cai, J Sun, R Guo, X Bi, WY Lau… - Liver cancer, 2020 - karger.com
Portal vein tumor thrombus (PVTT) is very common, and it plays a major role in the
prognosis and clinical staging of hepatocellular carcinoma (HCC). We have published the …