Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Optogenetics ushered in a revolution in how neuroscientists interrogate brain function.
Because of technical limitations, the majority of optogenetic studies have used low spatial …

Optogenetic methods provide efficient cell-specific modulations, and the ability of
simultaneous neural activation and inhibition in the same brain region of freely moving …

Disturbed neuronal activity in neuropsychiatric pathologies emerges during development
and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic …

Endothelial damage, astrogliosis, microgliosis, and neuronal degeneration are the most
common events after spinal cord injury (SCI). Studies highlighted that studying the …

The Medial Septum and diagonal Band of Broca (MSDB) was initially studied for its role in
locomotion. However, the last several decades were focussed on its intriguing function in …

Aureobasidium pullulans is a black fungus that can adapt to various stressful conditions like
hypersaline, acidic, and alkaline environments. The genome of A. pullulans exhibits three …

Low-power and high-frequency bidirectional control of spatiotemporal patterns of neural
spiking is one of the major challenges in optogenetics. A detailed theoretical analysis and …

Objective. A fundamental challenge in optogenetics is to elicit long-term high-fidelity
neuronal spiking with negligible heating. Fast channelrhodopsins (ChRs) require higher …

A fundamental challenge in the optogenetic toolbox is that all opsins, regardless of their
excitation spectra, are activated by blue light. We hypothesized that pairing a red-shifted …