The role of insulin resistance and diabetes in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) consists of the entire spectrum of fatty liver disease
in patients without significant alcohol consumption, ranging from nonalcoholic fatty liver …
in patients without significant alcohol consumption, ranging from nonalcoholic fatty liver …
[HTML][HTML] Novel biomarkers for the management of chronic hepatitis B
T Inoue, Y Tanaka - Clinical and molecular hepatology, 2020 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) cannot be eliminated completely from infected hepatocytes because
of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis …
of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis …
Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis
K Shirabe, Y Bekki, D Gantumur, K Araki, N Ishii… - Journal of …, 2018 - Springer
Assessing liver fibrosis is important for predicting the efficacy of antiviral therapy and patient
prognosis. Liver biopsy is the gold standard for diagnosing liver fibrosis, despite its …
prognosis. Liver biopsy is the gold standard for diagnosing liver fibrosis, despite its …
Effect of luseogliflozin on hepatic fat content in type 2 diabetes patients with non‐alcoholic fatty liver disease: a prospective, single‐arm trial (LEAD trial)
Y Sumida, K Murotani, M Saito… - Hepatology …, 2019 - Wiley Online Library
Aims No pharmacological therapies are approved for non‐alcoholic fatty liver disease
(NAFLD). Luseogliflozin, a sodium glucose cotransporter 2 inhibitor, has been developed for …
(NAFLD). Luseogliflozin, a sodium glucose cotransporter 2 inhibitor, has been developed for …
Skeletal muscle mass influences tolerability and prognosis in hepatocellular carcinoma patients treated with lenvatinib
H Uojima, M Chuma, Y Tanaka, H Hidaka, T Nakazawa… - Liver cancer, 2020 - karger.com
Background: Low skeletal muscle mass is significantly associated with severe adverse
events (AEs) from chemotherapy, and low tolerability leads to decreased survival. We aimed …
events (AEs) from chemotherapy, and low tolerability leads to decreased survival. We aimed …
Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein level predicts liver fibrosis and prognosis in primary biliary cirrhosis
OBJECTIVES: Noninvasive markers of liver fibrosis in patients with primary biliary cirrhosis
(PBC) are needed for predicting disease progression. As theWisteria floribundaagglutinin …
(PBC) are needed for predicting disease progression. As theWisteria floribundaagglutinin …
Oxidative stress in non-alcoholic fatty liver disease
C Smirne, E Croce, D Di Benedetto, V Cantaluppi… - Livers, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it still remains an orphan of adequate therapies. This …
factors, which may partly explain why it still remains an orphan of adequate therapies. This …
Multiparametric US for identifying patients with high-risk NASH: a derivation and validation study
K Sugimoto, DH Lee, JY Lee, SJ Yu, F Moriyasu… - Radiology, 2021 - pubs.rsna.org
Background Nonalcoholic fatty liver disease (NAFLD) is common in the general population
but identifying patients with high-risk nonalcoholic steatohepatitis (NASH) who are …
but identifying patients with high-risk nonalcoholic steatohepatitis (NASH) who are …
Hepatic stellate cells secreting WFA+‐M2BP: Its role in biological interactions with Kupffer cells
Y Bekki, T Yoshizumi, S Shimoda, S Itoh… - Journal of …, 2017 - Wiley Online Library
Abstract Background and Aim Hepatic stellate cells (HSCs) play a central role in hepatic
fibrosis and are regulated by Kupffer cells (KCs). Wisteria floribunda agglutinin‐positive Mac …
fibrosis and are regulated by Kupffer cells (KCs). Wisteria floribunda agglutinin‐positive Mac …
[HTML][HTML] Serum biomarkers for liver fibrosis
Z Chen, Y Ma, J Cai, M Sun, L Zeng, F Wu, Y Zhang… - Clinica Chimica …, 2022 - Elsevier
Liver fibrosis is a common pathway in most chronic liver diseases, characterized by
excessive extracellular matrix accumulation. Without treatment, fibrosis will ultimately result …
excessive extracellular matrix accumulation. Without treatment, fibrosis will ultimately result …