A review of the various synthetic approaches to access aurone derivatives and their biological activities

E Lathwal, S Kumar - Current Organic Chemistry, 2023 - ingentaconnect.com
Aurones, a member of the flavonoid family, have limited occurrence in nature and are
relatively less explored than other flavonoids but still constitute a gleaming class of …

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as …

MR Patel, A Bhatt, JD Steffen, A Chergui… - Journal of medicinal …, 2014 - ACS Publications
Novel substituted 2, 3-dihydrobenzofuran-7-carboxamide (DHBF-7-carboxamide) and 2, 3-
dihydrobenzofuran-3 (2 H)-one-7-carboxamide (DHBF-3-one-7-carboxamide) derivatives …

Structural aspects of flavonoids as trypsin inhibitors

T Maliar, A Jedinák, J Kadrabová, E Šturdík - European journal of medicinal …, 2004 - Elsevier
In the search for new proteinase inhibitors we have focused on the screening and Computer
Assisted Drug Design (CADD) studies of polyphenolic compounds. In this paper we report …

Synthesis and structure–activity relationship analysis of caffeic acid amides as selective matrix metalloproteinase inhibitors

ZH Shi, NG Li, QP Shi, H Tang, YP Tang, W Li… - Bioorganic & Medicinal …, 2013 - Elsevier
Four series of acid amides were synthesized, and through measurement using a fluorogenic
substrate assay with human recombinant MMP-1, MMP-2 and MMP-9, compound 3f showed …

Synthesis and Biological Evaluation of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitors Based on a Thieno[2,3-d]pyrimidin-4(3H)-one Core

A Lilienkampf, S Karkola… - Journal of medicinal …, 2009 - ACS Publications
Many breast tumors are hormone-dependent, and estrogens, especially estradiol (E2), have
a pivotal role in their growth and development. 17β-Hydroxysteroid dehydrogenase type 1 …

Far‐red‐to NIR‐emitting adamantyl‐functionalized squaraine dye: J‐aggregation, dissociation, and cell imaging

T Liu, X Liu, Y Zhang, MV Bondar… - European Journal of …, 2018 - Wiley Online Library
Squaraine dyes AM‐1′ and AM‐1 bearing adamantyl termini were synthesized and
spectroscopically characterized. AM‐1′ exhibited intense absorption and sharp emission in …

Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors

C Brullo, M Massa, C Villa, R Ricciarelli… - Bioorganic & Medicinal …, 2015 - Elsevier
A new series of selective PDE4D inhibitors has been designed and synthesized by
replacing 3-methoxy group with 3-difluoromethoxy isoster moiety in our previously reported …

Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime …

C Brullo, M Massa, M Rocca, C Rotolo… - Journal of Medicinal …, 2014 - ACS Publications
A new series of 3-(cyclopentyloxy)-4-methoxyphenyl derivatives, structurally related to our
hit GEBR-4a (1) and GEBR-7b (2), has been designed by changing length and functionality …

Diphenylmorpholine CMPO: Synthesis, coordination behavior and extraction studies of actinides

D Das, A Sivaramakrishna, G Gopakumar, CVSB Rao… - Polyhedron, 2018 - Elsevier
Carbamoylmethyl phosphine oxide (CMPO) derivatives are well known ligands in the
separation and extraction of trivalent lanthanides and actinides from nuclear waste. The …

Proteinase inhibition and antioxidant activity of selected forage crops

T Maliar, J Drobná, J Kraic, M Maliarová, J Jurovatá - Biologia, 2011 - degruyter.com
The hypothesis of the possible therapeutic potential of selected species of forage crops is
discussed. Extracts from genotypes of Anthyllis sp., Astragalus sp., Coronilla sp., Lotus sp …