A review of the various synthetic approaches to access aurone derivatives and their biological activities
E Lathwal, S Kumar - Current Organic Chemistry, 2023 - ingentaconnect.com
Aurones, a member of the flavonoid family, have limited occurrence in nature and are
relatively less explored than other flavonoids but still constitute a gleaming class of …
relatively less explored than other flavonoids but still constitute a gleaming class of …
Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as …
MR Patel, A Bhatt, JD Steffen, A Chergui… - Journal of medicinal …, 2014 - ACS Publications
Novel substituted 2, 3-dihydrobenzofuran-7-carboxamide (DHBF-7-carboxamide) and 2, 3-
dihydrobenzofuran-3 (2 H)-one-7-carboxamide (DHBF-3-one-7-carboxamide) derivatives …
dihydrobenzofuran-3 (2 H)-one-7-carboxamide (DHBF-3-one-7-carboxamide) derivatives …
Structural aspects of flavonoids as trypsin inhibitors
In the search for new proteinase inhibitors we have focused on the screening and Computer
Assisted Drug Design (CADD) studies of polyphenolic compounds. In this paper we report …
Assisted Drug Design (CADD) studies of polyphenolic compounds. In this paper we report …
Synthesis and structure–activity relationship analysis of caffeic acid amides as selective matrix metalloproteinase inhibitors
ZH Shi, NG Li, QP Shi, H Tang, YP Tang, W Li… - Bioorganic & Medicinal …, 2013 - Elsevier
Four series of acid amides were synthesized, and through measurement using a fluorogenic
substrate assay with human recombinant MMP-1, MMP-2 and MMP-9, compound 3f showed …
substrate assay with human recombinant MMP-1, MMP-2 and MMP-9, compound 3f showed …
Synthesis and Biological Evaluation of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitors Based on a Thieno[2,3-d]pyrimidin-4(3H)-one Core
A Lilienkampf, S Karkola… - Journal of medicinal …, 2009 - ACS Publications
Many breast tumors are hormone-dependent, and estrogens, especially estradiol (E2), have
a pivotal role in their growth and development. 17β-Hydroxysteroid dehydrogenase type 1 …
a pivotal role in their growth and development. 17β-Hydroxysteroid dehydrogenase type 1 …
Far‐red‐to NIR‐emitting adamantyl‐functionalized squaraine dye: J‐aggregation, dissociation, and cell imaging
Squaraine dyes AM‐1′ and AM‐1 bearing adamantyl termini were synthesized and
spectroscopically characterized. AM‐1′ exhibited intense absorption and sharp emission in …
spectroscopically characterized. AM‐1′ exhibited intense absorption and sharp emission in …
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors
C Brullo, M Massa, C Villa, R Ricciarelli… - Bioorganic & Medicinal …, 2015 - Elsevier
A new series of selective PDE4D inhibitors has been designed and synthesized by
replacing 3-methoxy group with 3-difluoromethoxy isoster moiety in our previously reported …
replacing 3-methoxy group with 3-difluoromethoxy isoster moiety in our previously reported …
Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime …
C Brullo, M Massa, M Rocca, C Rotolo… - Journal of Medicinal …, 2014 - ACS Publications
A new series of 3-(cyclopentyloxy)-4-methoxyphenyl derivatives, structurally related to our
hit GEBR-4a (1) and GEBR-7b (2), has been designed by changing length and functionality …
hit GEBR-4a (1) and GEBR-7b (2), has been designed by changing length and functionality …
Diphenylmorpholine CMPO: Synthesis, coordination behavior and extraction studies of actinides
Carbamoylmethyl phosphine oxide (CMPO) derivatives are well known ligands in the
separation and extraction of trivalent lanthanides and actinides from nuclear waste. The …
separation and extraction of trivalent lanthanides and actinides from nuclear waste. The …
Proteinase inhibition and antioxidant activity of selected forage crops
The hypothesis of the possible therapeutic potential of selected species of forage crops is
discussed. Extracts from genotypes of Anthyllis sp., Astragalus sp., Coronilla sp., Lotus sp …
discussed. Extracts from genotypes of Anthyllis sp., Astragalus sp., Coronilla sp., Lotus sp …