Autophagy and cancer drug resistance in dialogue: pre-clinical and clinical evidence
Y Qin, M Ashrafizadeh, V Mongiardini, B Grimaldi… - Cancer letters, 2023 - Elsevier
The emergence of drug resistance is a major challenge for oncologists. Resistance can be
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
Nanomaterials in tumor immunotherapy: new strategies and challenges
X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …
responses of the body. It has become another important modality of anti-tumor therapy with …
Exosomal circRNA: emerging insights into cancer progression and clinical application potential
F Zhang, J Jiang, H Qian, Y Yan, W Xu - Journal of Hematology & …, 2023 - Springer
Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …
Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
[HTML][HTML] Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges
MDA Paskeh, F Ghadyani, M Hashemi… - Pharmacological …, 2023 - Elsevier
Cancer progression results from activation of various signaling networks. Among these,
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
Extracellular vesicles remodel tumor environment for cancer immunotherapy
M Yue, S Hu, H Sun, B Tuo, B Jia, C Chen, W Wang… - Molecular Cancer, 2023 - Springer
Tumor immunotherapy has transformed neoplastic disease management, yet low response
rates and immune complications persist as major challenges. Extracellular vesicles …
rates and immune complications persist as major challenges. Extracellular vesicles …
[HTML][HTML] Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment
Natural compounds are widely used to prevent and treat various diseases due to their
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …
Engineering extracellular vesicles as delivery systems in therapeutic applications
L Wang, D Wang, Z Ye, J Xu - Advanced Science, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …
Involvement of lncRNAs in cancer cells migration, invasion and metastasis: cytoskeleton and ECM crosstalk
Cancer is the main cause of death worldwide and metastasis is a major cause of poor
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …