Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer

R Stading, G Gastelum, C Chu, W Jiang… - Seminars in cancer …, 2021 - Elsevier
Lung cancer has the second highest incidence and highest mortality compared to all other
cancers. Polycyclic aromatic hydrocarbon (PAH) molecules belong to a class of compounds …

Air pollution: A culprit of lung cancer

Y Xue, L Wang, Y Zhang, Y Zhao, Y Liu - Journal of hazardous materials, 2022 - Elsevier
Air pollution is a global health problem, especially in the context of rapid economic
development and the expansion of urbanization. Herein, we discuss the harmful effects of …

[HTML][HTML] Distribution, risk factors, and temporal trends for lung cancer incidence and mortality: a global analysis

J Huang, Y Deng, MS Tin, V Lok, CH Ngai, L Zhang… - Chest, 2022 - Elsevier
Background Lung cancer ranks second for cancer incidence and first for cancer mortality.
Investigation into its risk factors and epidemiologic trends could help describe geographical …

Role of the NLRP3 inflammasome in cancer

M Moossavi, N Parsamanesh, A Bahrami, SL Atkin… - Molecular cancer, 2018 - Springer
Inflammasomes are large intracellular multi-protein signalling complexes that are formed in
the cytosolic compartment as an inflammatory immune response to endogenous danger …

Lung cancers: molecular characterization, clonal heterogeneity and evolution, and cancer stem cells

U Testa, G Castelli, E Pelosi - Cancers, 2018 - mdpi.com
Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …

Cancer incidence and trends

MC Hulvat - Surgical Clinics, 2020 - surgical.theclinics.com
Cancer is the second leading cause of death worldwide and in North America, behind only
ischemic heart disease. 1, 2 However, a recent prospective, population-based cohort study …

[HTML][HTML] Global trends of bladder cancer incidence and mortality, and their associations with tobacco use and gross domestic product per capita

JYC Teoh, J Huang, WYK Ko, V Lok, P Choi, CF Ng… - European urology, 2020 - Elsevier
Background Bladder cancer is a major urological disease, with approximately 550 000 new
cases diagnosed in 2018. Objective We examined gender-specific incidence and mortality …

MEG3: an oncogenic long non-coding RNA in different cancers

A Al-Rugeebah, M Alanazi, NR Parine - Pathology & Oncology Research, 2019 - Springer
Long noncoding RNAs (lncRNAs) have recently considered as central regulators in diverse
biological processes and emerged as vital players controlling tumorigenesis. Several …

Anticancer effects of fucoxanthin through cell cycle arrest, apoptosis induction, angiogenesis inhibition, and autophagy modulation

SA Ahmed, P Mendonca, R Elhag… - International Journal of …, 2022 - mdpi.com
Cancer accounts for one in seven deaths worldwide and is the second leading cause of
death in the United States, after heart disease. One of the standard cancer treatments is …

TGF-β1/SH2B3 axis regulates anoikis resistance and EMT of lung cancer cells by modulating JAK2/STAT3 and SHP2/Grb2 signaling pathways

LN Wang, ZT Zhang, L Wang, HX Wei, T Zhang… - Cell death & …, 2022 - nature.com
The pathogenesis of lung cancer, the most common cancer, is complex and unclear, leading
to limited treatment options and poor prognosis. To provide molecular insights into lung …