SGLT2 inhibitors: mechanisms of cardiovascular benefit beyond glycaemic control
Abstract Sodium–glucose cotransporter 2 (SGLT2) inhibitors are effective antidiabetic
therapies in patients with type 2 diabetes mellitus and are associated with improved …
therapies in patients with type 2 diabetes mellitus and are associated with improved …
Adipose tissue dysfunction as determinant of obesity-associated metabolic complications
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging
Diabesity is a term used to describe the combined adverse health effects of obesity and
diabetes mellitus. The worldwide dual epidemic of obesity and type 2 diabetes is an …
diabetes mellitus. The worldwide dual epidemic of obesity and type 2 diabetes is an …
Mechanistic insights of empagliflozin in nondiabetic patients with HFrEF: from the EMPA-TROPISM study
JA Requena-Ibáñez, CG Santos-Gallego… - Heart Failure, 2021 - jacc.org
Objectives The goal of this study was to evaluate the effect of empagliflozin, in addition to
optimal medical treatment, on epicardial adipose tissue (EAT), interstitial myocardial fibrosis …
optimal medical treatment, on epicardial adipose tissue (EAT), interstitial myocardial fibrosis …
Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes
L Staerk, JA Sherer, D Ko, EJ Benjamin… - Circulation …, 2017 - Am Heart Assoc
The past 3 decades have been characterized by an exponential growth in knowledge and
advances in the clinical treatment of atrial fibrillation (AF). It is now known that AF genesis …
advances in the clinical treatment of atrial fibrillation (AF). It is now known that AF genesis …
Hemodynamic and functional impact of epicardial adipose tissue in heart failure with preserved ejection fraction
Objectives This study determined the impact of excess epicardial adipose tissue (EAT) in
patients with the obese phenotype of heart failure with preserved ejection fraction (HFpEF) …
patients with the obese phenotype of heart failure with preserved ejection fraction (HFpEF) …
Local and systemic effects of the multifaceted epicardial adipose tissue depot
G Iacobellis - Nature Reviews Endocrinology, 2015 - nature.com
Epicardial adipose tissue is a unique and multifaceted fat depot with local and systemic
effects. This tissue is distinguished from other visceral fat depots by a number of anatomical …
effects. This tissue is distinguished from other visceral fat depots by a number of anatomical …
[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction
AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …
expanding. Just in the past decade, substantial advances have led to new insights into the …
Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines
N Venteclef, V Guglielmi, E Balse, B Gaborit… - European heart …, 2015 - academic.oup.com
Aims Recent studies have reported a relationship between the abundance of epicardial
adipose tissue (EAT) and the risk of cardiovascular diseases including atrial fibrillation (AF) …
adipose tissue (EAT) and the risk of cardiovascular diseases including atrial fibrillation (AF) …
Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis
G Livshits, A Kalinkovich - Ageing research reviews, 2019 - Elsevier
Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …