Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Neutrophils are rapidly recruited to sites of mycobacterial infection, where they phagocytose
bacilli. Whether neutrophils can kill mycobacteria in vivo probably depends on the tissue …

The innate immune system is the first line of defense against many common
microorganisms, which can initiate adaptive immune responses to provide increased …

The genome sequence of Mycobacterium tuberculosis revealed the presence of 12
membrane proteins proposed to have a function in the transport of lipids. Insertional …

Microbial infections from post-surgery or other medical-related procedure is a serious health
problem. Nowadays, the research is focused on the development of new drug-free materials …

The innate immune response in human tuberculosis is not completely understood. To
improve our knowledge regarding the role of cathelicidin hCAP-18/LL37 in the innate …

Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …

Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …

Tuberculosis (TB), an infectious disease caused by the pathogen Mycobacterium
tuberculosis (Mtb), kills about 1.5 million people every year worldwide. An increase in the …