Transient receptor potential melastatin 8 (TRPM8) is a cold-sensing thermoreceptor cation
channel; however, its functional role in endotoxin-induced neuroinflammation remains …

Transient receptor potential melastatin 8 (TRPM8) functions in the sensing of noxious and
innocuous colds; however, its significance in pathogen-induced thermoregulation remains …

Proteinase-activated receptor-2 (PAR2), which modulates inflammatory responses, is
elevated in the central nervous system in multiple sclerosis (MS) and in its murine model …

Aims To investigate the cardioprotective effects of hypothermic (25° C) reperfusion on
ischemia/reperfusion injury and the role of transient potential channel M8 (TRPM8) in this …

The frequently occurring neurological diseases with vascular and degenerative origin affect
millions of people worldwide. The pathologies cause extensive damage to neurons in …

Transient Receptor Potential (TRP) channels are a large and diverse family of tetrameric
cation selective channels that are activated by many different types of stimuli, including …

In dieser Arbeit wurde die Rolle der TRP-Kanäle hinsichtlich ihres Einflusses auf
Inflammation und Antiinflammation in synovialen Fibroblasten (SF) bei Patienten mit …

目的薄荷醇通过瞬时受体电位TRPM8 对炎症因子负调控作用的机制. 方法首先在整体动物实验,
检测薄荷醇对小鼠下丘脑中TRPM8, 核转录因子NF-κB 以及炎症因子TNF-α 表达水平的调控 …

Abstract Proteinase-activated receptor-2 (PAR2), which modulates inflammatory responses,
is elevated in the central nervous system (CNS) in multiple sclerosis (MS) and in its murine …

Uniquely essential to immunological propagation and memory, the adaptive arm of the
immune system plays a pivotal role in mammalian health. However, aberrant activation of …