The cerebellum is involved in many motor, autonomic and cognitive functions, and new
tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously …

Abstract Parkinson's disease (PD), or paralysis agitans, is a common neurodegenerative
disease characterized by dopaminergic deprivation in the basal ganglia because of …

Parkinson's disease (PD) is pathologically manifested by the aggregation of α-synuclein,
which has been envisioned as a promising disease-modifying target for PD. Here, we …

Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective treatment for
the motor symptoms of movement disorders including Parkinson's Disease (PD). Despite its …

Excessive self-grooming is an important behavioral phenotype of the stress response in
rodents. Elucidating the neural circuit that regulates stress-induced self-grooming may …

The loss-of-function S284L-mutant α4 subunit of the nicotinic acetylcholine receptor
(nAChR) is considered to contribute to the pathomechanism of autosomal dominant sleep …

To study the pathomechanism and pathophysiology of nocturnal paroxysmal dystonia of
autosomal dominant sleep-related hypermotor epilepsy (ADSHE), this study determined …

Deep-brain subthalamic nucleus stimulation (DBS-STN) has become a well-established
therapeutic option for advanced Parkinson's disease (PD). While the motor benefits of DBS …

Background: Implantable pulse generators (IPGs) store energy and deliver electrical
impulses for deep brain stimulation (DBS) to treat neurological and psychiatric disorders …

The brain is a remarkably complex organ responsible for a wide range of functions,
including the modulation of emotional states and movement. Neuronal circuits are believed …