The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Objective Ferroptosis is indicated in cardiovascular diseases. Given the prominent role of
mitophagy in the governance of ferroptosis and our recent finding for FUN14 domain …

Mitochondrial dysfunction has been implicated in the pathogenesis of nonalcoholic fatty liver
disease (NAFLD) through poorly defined mechanisms. Melatonin supplementation has been …

Trastuzumab (TZM) is commonly used for target therapy in breast cancer patients with high
HER2 although the cardiotoxicity restricts its clinical usage. DNA damage and ferroptosis …

The skeletal muscle is the largest organ in the body and secretes circulating factors,
including myokines, which are involved in various cellular signaling processes. Skeletal …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible
for coronavirus disease (COVID-19), potentially have severe kidney adverse effects. This …

Type 2 diabetes mellitus (T2D) contributes to sustained inflammation and myopathic
changes in the heart although the precise interplay between the two remains largely …

MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin
resistance and dyslipidemia. Research on its involvement in cardiovascular diseases has …