Autosomal dominant polycystic kidney disease

E Cornec-Le Gall, A Alam, RD Perrone - The Lancet, 2019 - thelancet.com
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease and one of the most common causes of end-stage kidney disease. Multiple …

[HTML][HTML] Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies …

AB Chapman, O Devuyst, KU Eckardt, RT Gansevoort… - Kidney international, 2015 - Elsevier
Autosomal-dominant polycystic kidney disease (ADPKD) affects up to 12 million individuals
and is the fourth most common cause for renal replacement therapy worldwide. There have …

Strategies targeting cAMP signaling in the treatment of polycystic kidney disease

VE Torres, PC Harris - Journal of the American Society of …, 2014 - journals.lww.com
Polycystic kidney disease (PKD) is a leading cause of ESRD worldwide. In PKD, excessive
cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with …

Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled …

A Caroli, N Perico, A Perna, L Antiga, P Brambilla… - The Lancet, 2013 - thelancet.com
Background Autosomal dominant polycystic kidney disease slowly progresses to end-stage
renal disease and has no effective therapy. A pilot study suggested that the somatostatin …

Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management

WR Cnossen, JPH Drenth - Orphanet journal of rare diseases, 2014 - Springer
Polycystic liver disease (PLD) is the result of embryonic ductal plate malformation of the
intrahepatic biliary tree. The phenotype consists of numerous cysts spread throughout the …

Diagnosis and management of polycystic liver disease

TJG Gevers, JPH Drenth - Nature reviews Gastroenterology & …, 2013 - nature.com
Polycystic liver disease (PLD) is arbitrarily defined as a liver that contains> 20 cysts. The
condition is associated with two genetically distinct diseases: as a primary phenotype in …

[HTML][HTML] Evaluation of hepatic cystic lesions

MA Lantinga, TJG Gevers… - World journal of …, 2013 - ncbi.nlm.nih.gov
Hepatic cysts are increasingly found as a mere coincidence on abdominal imaging
techniques, such as ultrasonography (USG), computed tomography (CT) and magnetic …

Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD): considerations for routine screening and management

RL Luciano, NK Dahl - Nephrology Dialysis Transplantation, 2014 - academic.oup.com
Autosomal-dominant polycystic kidney disease (ADPKD) is a systemic disease, marked by
progressive increase of bilateral renal cysts, resulting in chronic kidney disease (CKD) and …

Effect of lanreotide on kidney function in patients with autosomal dominant polycystic kidney disease: the DIPAK 1 randomized clinical trial

E Meijer, FW Visser, RMM Van Aerts, CJ Blijdorp… - Jama, 2018 - jamanetwork.com
Importance Autosomal dominant polycystic kidney disease (ADPKD) is characterized by
progressive cyst formation in both kidneys and loss of renal function, eventually leading to a …

Polycystic liver disease: advances in understanding and treatment

TV Masyuk, AI Masyuk… - Annual Review of …, 2022 - annualreviews.org
Polycystic liver disease (PLD) is a group of genetic disorders characterized by progressive
development of cholangiocyte-derived fluid-filled hepatic cysts. PLD is the most common …