Without any exaggeration, cholesterol is one of the most important lipid species in eukaryotic
cells. Its effects on cellular membranes and functions range from purely mechanistic to …

Saponins, amphiphiles of natural origin with numerous biological activities, are widely used
in the cosmetic and pharmaceutical industry. Some saponins exhibit relatively selective …

The AMBER lipid force field has been updated to create Lipid14, allowing tensionless
simulation of a number of lipid types with the AMBER MD package. The modular nature of …

Critical fluctuations are investigated in lipid membranes near miscibility critical points in
bilayers composed of dioleoylphosphatidylcholine, chain perdeuterated …

Many plasma membrane (PM) functions depend on the cholesterol concentration in the PM
in strikingly nonlinear, cooperative ways: fully functional in the presence of physiological …

We report diffusion coefficients of micron-scale liquid domains in giant unilamellar vesicles
of phospholipids and cholesterol. The trajectory of each domain is tracked, and the mean …

It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

Using linewidth and spinning sideband intensities of lipid hydrocarbon chain resonances in
proton magic angle spinning NMR spectra, we detected the temperature-dependent phase …

Mixtures of phospholipids with cholesterol are able to form liquid-ordered phases that are
characterised by short-range orientational order and long-range translational disorder …

Long-range Lennard-Jones (LJ) interactions have been incorporated into the CHARMM36
(C36) lipid force field (FF) using the LJ particle-mesh Ewald (LJ-PME) method in order to …