Modern glioma surgery has evolved from the principal belief that safe, maximal tumor
resection improves symptom management, quality of life, progression-free survival, and …

Neurosurgery makes use of preoperative imaging to visualize pathology, inform surgical
planning, and evaluate the safety of selected approaches. The utility of preoperative imaging …

Glioblastomas (GBM), one of the most common tumors of the central nervous system, are
associated with poor prognosis, even with all the scientific development of the last decades …

Tumors of the central nervous system (CNS) constitute approximately 2% of all
malignancies. Although relatively rare, the associated morbidity and mortality and the …

The invasive capacity of GBM is one of the key tumoral features associated with treatment
resistance, recurrence, and poor overall survival. The molecular machinery underlying GBM …

Background Image-guided surgery has become standard practice during surgical resection,
using preoperative magnetic resonance imaging. Intraoperative ultrasound (IoUS) has …

Background Surgical resection of high-grade gliomas (HGG) is standard therapy because it
imparts significant progression free (PFS) and overall survival (OS). However, HGG-tumor …

Introduction: Glioma surgery is aimed at obtaining maximal safe tumor resection while
preserving or improving patient's neurological status. For this reason, there is growing …

The aggressive and recurrent nature of glioblastoma is multifactorial and has been attributed
to its biological heterogeneity, dysfunctional metabolic signaling pathways, rigid blood–brain …

Simple Summary Several advantages of molecular imaging, namely, positron emission
tomography (PET), have been already described in different settings of glioma management …