The immune response to influenza in older humans: beyond immune senescence

JE McElhaney, CP Verschoor, MK Andrew, L Haynes… - Immunity & …, 2020 - Springer
Despite widespread influenza vaccination programs, influenza remains a major cause of
morbidity and mortality in older adults. Age-related changes in multiple aspects of the …

Challenges in estimating influenza vaccine effectiveness

KEC Ainslie, M Haber, WA Orenstein - Expert review of vaccines, 2019 - Taylor & Francis
Introduction: Influenza vaccination is regarded as the most effective way to prevent influenza
infection. Due to the rapid genetic changes that influenza viruses undergo, seasonal …

Translation of a Claims-Based Frailty Index From the International Classification of Diseases, Ninth Revision, Clinical Modification to the Tenth Revision

ED Duchesneau, S Shmuel, KR Faurot… - American Journal of …, 2023 - academic.oup.com
The Faurot frailty index (FFI) is a validated algorithm that uses enrollment and International
Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM)–based billing …

[HTML][HTML] Measuring frailty in health care databases for clinical care and research

DH Kim - Annals of geriatric medicine and research, 2020 - ncbi.nlm.nih.gov
Considering the increasing burden and serious consequences of frailty in aging
populations, there is increasing interest in measuring frailty in health care databases for …

The importance and implications of comparator selection in pharmacoepidemiologic research

M D'Arcy, T Stürmer, JL Lund - Current epidemiology reports, 2018 - Springer
Purpose of review Pharmacoepidemiologic studies employing large databases are critical to
evaluating the effectiveness and safety of drug exposures in large and diverse populations …

Assessing the benefits and harms of pharmacotherapy in older adults with frailty: insights from pharmacoepidemiologic studies of routine health care data

DH Kim, CM Park, D Ko, KJ Lin, RJ Glynn - Drugs & Aging, 2024 - Springer
The objective of this review is to summarize and appraise the research methodology,
emerging findings, and future directions in pharmacoepidemiologic studies assessing the …

Performance of a claims-based frailty proxy using varying frailty ascertainment lookback windows

ED Duchesneau, T Stürmer, DH Kim… - Medical …, 2024 - journals.lww.com
Background: Frailty is an aging-related syndrome of reduced physiological reserve to
maintain homeostasis. The Faurot frailty index has been validated as a Medicare claims …

The State of Use and Utility of Negative Controls in Pharmacoepidemiologic Studies

Z Zafari, J Park, CH Shah, S Dosreis… - American Journal of …, 2024 - academic.oup.com
Uses of real-world data in drug safety and effectiveness studies are often challenged by
various sources of bias. We undertook a systematic search of the published literature …

Development of an administrative data-based frailty index for older adults receiving dialysis

RK Hall, S Morton, J Wilson, DH Kim… - Kidney360, 2022 - journals.lww.com
Background Frailty is present in≥ 50% of older adults receiving dialysis. Our objective was
to a develop an administrative data–based frailty index and assess the frailty index's …

Longitudinal changes in a claims-based frailty proxy measure compared to concurrent changes in the Fried frailty phenotype

ED Duchesneau, DH Kim, T Stürmer… - The Journals of …, 2024 - academic.oup.com
Background Frailty is a dynamic aging-related syndrome, but measuring frailty transitions is
challenging. The Faurot frailty index is a validated Medicare claims-based frailty proxy …