The mechanisms of vesicle budding and fusion
JS Bonifacino, BS Glick - cell, 2004 - cell.com
Genetic and biochemical analyses of the secretory pathway have produced a detailed
picture of the molecular mechanisms involved in selective cargo transport between …
picture of the molecular mechanisms involved in selective cargo transport between …
Signaling mechanisms regulating endothelial permeability
D Mehta, AB Malik - Physiological reviews, 2006 - journals.physiology.org
The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and
diabetes. Akt/PKB activation requires the phosphorylation of Thr308 in the activation loop by …
diabetes. Akt/PKB activation requires the phosphorylation of Thr308 in the activation loop by …
[HTML][HTML] Membrane fusion
R Jahn, T Lang, TC Südhof - Cell, 2003 - cell.com
Membrane fusion, one of the most fundamental processes in life, occurs when two separate
lipid membranes merge into a single continuous bilayer. Fusion reactions share common …
lipid membranes merge into a single continuous bilayer. Fusion reactions share common …
The exocyst at a glance
B Wu, W Guo - Journal of cell science, 2015 - journals.biologists.com
The exocyst is an octameric protein complex that is implicated in the tethering of secretory
vesicles to the plasma membrane prior to SNARE-mediated fusion. Spatial and temporal …
vesicles to the plasma membrane prior to SNARE-mediated fusion. Spatial and temporal …
Chaperoning SNARE assembly and disassembly
RW Baker, FM Hughson - Nature reviews Molecular cell biology, 2016 - nature.com
Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …
Structural basis of mitochondrial tethering by mitofusin complexes
T Koshiba, SA Detmer, JT Kaiser, H Chen… - Science, 2004 - science.org
Vesicle fusion involves vesicle tethering, docking, and membrane merger. We show that
mitofusin, an integral mitochondrial membrane protein, is required on adjacent mitochondria …
mitofusin, an integral mitochondrial membrane protein, is required on adjacent mitochondria …
Rab proteins: the key regulators of intracellular vesicle transport
T Bhuin, JK Roy - Experimental cell research, 2014 - Elsevier
Vesicular/membrane trafficking essentially regulates the compartmentalization and
abundance of proteins within the cells and contributes in many signalling pathways. This …
abundance of proteins within the cells and contributes in many signalling pathways. This …
Bi-directional protein transport between the ER and Golgi
▪ Abstract The endoplasmic reticulum (ER) and the Golgi comprise the first two steps in
protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between …
protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between …
Tethering the assembly of SNARE complexes
WJ Hong, S Lev - Trends in cell biology, 2014 - cell.com
The fusion of transport vesicles with their target membranes is fundamental for intracellular
membrane trafficking and diverse physiological processes and is driven by the assembly of …
membrane trafficking and diverse physiological processes and is driven by the assembly of …