Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

Y Shi, Y Wang, Q Li, K Liu, J Hou, C Shao… - Nature Reviews …, 2018 - nature.com
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …

[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Corneal neovascularization

MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …

MSCs and inflammatory cells crosstalk in regenerative medicine: concerted actions for optimized resolution driven by energy metabolism

V Planat-Benard, A Varin, L Casteilla - Frontiers in immunology, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy
regarding to their remarkable efficacy in controlling the inflammatory status in patients …

Cell–cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models

Y Li, D Zhang, L Xu, L Dong, J Zheng, Y Lin… - Cellular & molecular …, 2019 - nature.com
Mesenchymal stem cells (MSCs), which are pluripotent cells with immunomodulatory
properties, have been considered good candidates for the therapy of several immune …

Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling …

H Yang, L Wu, H Deng, Y Chen, H Zhou, M Liu… - Journal of …, 2020 - Springer
Background Neuroinflammation plays a vital role in the development and maintenance of
neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells …

Mesenchymal stem cells: A living carrier for active tumor-targeted delivery

T Zhang, R Lin, H Wu, X Jiang, J Gao - Advanced Drug Delivery Reviews, 2022 - Elsevier
The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …

Corneal wound healing effects of mesenchymal stem cell secretome delivered within a viscoelastic gel carrier

GM Fernandes-Cunha, KS Na, I Putra… - Stem cells …, 2019 - academic.oup.com
Severe corneal injuries often result in permanent vision loss and remain a clinical challenge.
Human bone marrow-derived mesenchymal stem cells (MSCs) and their secreted factors …

Current trends and future perspective of mesenchymal stem cells and exosomes in corneal diseases

H Mansoor, HS Ong, AK Riau, TP Stanzel… - International journal of …, 2019 - mdpi.com
The corneal functions (transparency, refractivity and mechanical strength) deteriorate in
many corneal diseases but can be restored after corneal transplantation (penetrating and …

TWIST1 and TSG6 are coordinately regulated and function as potency biomarkers in human MSCs

RH Lee, SV Boregowda, T Shigemoto-Kuroda… - Science …, 2023 - science.org
Mesenchymal stem/stromal cells (MSCs) have been evaluated in> 1500 clinical trials, but
outcomes remain suboptimal because of knowledge gaps in quality attributes that confer …