Ocular drug delivery to the retina: current innovations and future perspectives

HM Kim, SJ Woo - Pharmaceutics, 2021 - mdpi.com
Treatment options for retinal diseases, such as neovascular age-related macular
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …

[HTML][HTML] Ocular drug delivery systems: An overview

A Patel, K Cholkar, V Agrahari… - World journal of …, 2013 - ncbi.nlm.nih.gov
The major challenge faced by today's pharmacologist and formulation scientist is ocular
drug delivery. Topical eye drop is the most convenient and patient compliant route of drug …

Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application

CH Tsai, PY Wang, IC Lin, H Huang, GS Liu… - International journal of …, 2018 - mdpi.com
Ocular drug delivery has been a major challenge for clinical pharmacologists and
biomaterial scientists due to intricate and unique anatomical and physiological barriers in …

Ocular delivery of proteins and peptides: Challenges and novel formulation approaches

A Mandal, D Pal, V Agrahari, HM Trinh… - Advanced drug delivery …, 2018 - Elsevier
The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …

Drug delivery to the eye: what benefits do nanocarriers offer?

RR Joseph, SS Venkatraman - Nanomedicine, 2017 - Taylor & Francis
Ocular drug delivery has seen several advances in the past few decades, with respect to
new drugs, improved formulations, targeted delivery, as well as exploration of new routes of …

Sustained-release from nanocarriers: a review

JV Natarajan, C Nugraha, XW Ng… - Journal of Controlled …, 2014 - Elsevier
Nanocarriers have been explored for delivering drugs and other bioactive molecules for well
over 35 years. Since the introduction of Doxil®, a nanoliposomal delivery system for the …

An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

[PDF][PDF] Progress and challenges of anti-VEGF agents and their sustained-release strategies for retinal angiogenesis

M Xu, R Fan, X Fan, Y Shao, X Li - Drug design, development and …, 2023 - Taylor & Francis
Currently, the treatment for ocular neovascular diseases, including diabetic macular edema
(DME) and age-related macular degeneration (AMD), mainly involves repeated intravitreal …

Liposomes for intravitreal drug delivery: a state of the art

A Bochot, E Fattal - Journal of Controlled Release, 2012 - Elsevier
Intravitreal administration of drugs has raised a large interest during the last two decades
improving the treatment of infectious diseases of the posterior segment of the eye or …

Recent applications of liposomes in ophthalmic drug delivery

GP Mishra, M Bagui, V Tamboli… - Journal of drug …, 2011 - Wiley Online Library
Liposomal formulations were significantly explored over the last decade for the ophthalmic
drug delivery applications. These formulations are mainly composed of phosphatidylcholine …