In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …

Metal-based compounds form a promising class of therapeutic agents, whose mechanisms
of action still need to be elucidated, and that are in general prone to undergo extensive …

The reaction of gold reagents [HAuCl4• 3H2O],[AuCl (tht)], or cyclometalated gold (III)
precursor,[C^ NAuCl2] with chiral ((R, R)-(-)-2, 3-bis (t-butylmethylphosphino) quinoxaline) …

Phosphines are the most studied ligands on gold-based metallodrugs, whereas N-
heterocyclic carbenes (NHCs) have been emerging in the past years as potential alternative …

Zinc finger proteins are one of the most abundant families of proteins and present a wide
range of structures and functions. The structural zinc ion provides the correct conformation to …

Zinc finger proteins are abundant in the human proteome and are responsible for a variety of
functions. The domains that constitute zinc finger proteins are compact spherical structures …

Gold (I) N-heterocyclic carbenes have been explored for their therapeutic potential against
several diseases. Neglected tropical diseases, including leishmaniasis, Chagas disease …

The binding of Au (III) complexes to the zinc finger domain of the anticancer drug target
PARP-1 was studied using a hyphenated mass spectrometry approach combined with …

The development of metal‐based anticancer drugs has been hampered, among other
reasons, by their lack of selectivity for cancer cells. In a recent article, Zou and co‐workers …

Curcumin (CUR) is one natural bioactive compound acknowledged for diverse therapeutic
activities, but its use is hindered by its poor bioavailability, fast metabolism, and susceptibility …