The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Understanding the diversity of dynamic structures and functions of DNA and RNA in biology
requires tools that can selectively and intimately probe these biomolecules. Synthetic …

A near-neutral pH near-infrared (NIR) fluorescent probe utilizing a fluorophore-spacer-
receptor molecular framework that can modulate the fluorescence emission intensity through …

The availability of synthetic fluorescent probes and the development of powerful new
approaches to microscopy have made fluorescence microscopy an essential tool for …

pH plays an important role in understanding physiological/pathologic processes, and
abnormal pH is a symbol of many common diseases such as cancer, stroke, and Alzheimer's …

We constructed a series of novel optical sensors for determination of broad-range pH based
on a single fluorophore and multi-ionophores with different p K a values. These optical …

A novel acidic fluorescent probe 1 has been designed, synthesized, characterized and
evaluated in vivo as optical imaging of intracellular H+. The design strategy for the probe is …

A simple, fast and low-cost method for dopamine (DA) detection based on turn-on
fluorescence using resorcinol is developed. The rapid reaction between resorcinol and DA …

We report two-photon (TP) pH probes (AH1, AH2) and a TP lysotracker (AL1, Scheme 1)
derived from 2-acetyl-6-(dimethylamino) naphthalene (acedan). These probes can visualize …