Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

[HTML][HTML] Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights

SA Mason, AJ Trewin, L Parker, GD Wadley - Redox biology, 2020 - Elsevier
Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Aerobic exercise training and vascular function with ageing in healthy men and women

DR Seals, EE Nagy, KL Moreau - The Journal of physiology, 2019 - Wiley Online Library
Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in both
men and women in developed societies. Age is the greatest risk factor for CVD due largely …

Polyphenols: benefits to the cardiovascular system in health and in aging

S Khurana, K Venkataraman, A Hollingsworth, M Piche… - Nutrients, 2013 - mdpi.com
Numerous studies have demonstrated the importance of naturally occurring dietary
polyphenols in promoting cardiovascular health and emphasized the significant role these …

Comparative absorption of curcumin formulations

R Jäger, RP Lowery, AV Calvanese, JM Joy, M Purpura… - Nutrition journal, 2014 - Springer
Background The potential health benefits of curcumin are limited by its poor solubility, low
absorption from the gut, rapid metabolism and rapid systemic elimination. The purpose of …

The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

C Schiborr, A Kocher, D Behnam… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Curcumin revealed various health‐beneficial properties in numerous studies.
However its bioavailability is low due to its limited intestinal uptake and rapid metabolism …