There is currently an unmet need for better biomarkers across the spectrum of renal
diseases. In this paper, we revisit the role of beta-2 microglobulin (β2M) as a biomarker in …

Background Myoglobin clearance in acute kidney injury requiring renal replacement therapy
is important because myoglobin has direct renal toxic effects. Clinical data comparing …

The aim of this study was to delve into whether beta‐2 microglobulin could assess all‐cause
mortality in patients with chronic kidney disease. PubMed and Embase were systematically …

Introduction: Classic hemodialysis schedules present inadequate middle-molecular-weight
toxin clearance due to limitations of membrane-based separation processes. Accumulation …

Results During a mean follow-up of 42 months, 385 (19.8%) patients died. In multivariable
Cox analyses, residual urine volume (hazard ratio, 0.96 per 0.1-L/d higher volume; 95 …

Background Most patients on hemodialysis are treated thrice weekly even if they have
residual kidney function, in part because uncertainty remains as to how residual function …

Background Worldwide obesity spread is a global health problem and needs to be further
studied. Co-morbidities of obesity include insulin resistance, diabetes mellitus type 2, and …

Background Regional anticoagulation with citrate during renal replacement therapy (RRT)
reduces the risk of bleeding, extends dialyzer lifespan and is cost-effective. Therefore …

In this study, we evaluate the in vivo clinical performances of CorDiax FX 100 and CorDiax
FX 1000 filters incorporating a high-flux membrane (Helixone Plus) designed for use in high …

Background: Residual kidney function (RKF) is often expected to inevitably and rapidly
decline among hemodialysis patients and, hence, has been inadvertently ignored in clinical …