The hnRNPs (heterogeneous nuclear ribonucleoproteins) are RNA-binding proteins with
important roles in multiple aspects of nucleic acid metabolism, including the packaging of …

Significance: Normal wound healing progresses through a series of overlapping phases, all
of which are coordinated and regulated by a variety of molecules, including chemokines …

Background Exosomes, derived from endocytic membrane vesicles are thought to
participate in cell-cell communication and protein and RNA delivery. They are ubiquitous in …

The discovery of disease-specific biomarkers in oral fluids has revealed a new dimension in
molecular diagnostics. Recent studies have reported the mechanistic involvement of tumor …

Cytokines are critical mediators of inflammation and host defenses. Regulation of cytokines
can occur at various stages of gene expression, including transcription, mRNA export, and …

Although it is widely accepted that sleep must serve an essential biological function, little is
known about molecules that underlie sleep regulation. Given that insomnia is a common …

Background Saliva (oral fluids) is an emerging biofluid poised for detection of clinical
diseases. Although the rationale for oral diseases applications (eg oral cancer) is intuitive …

HuR is a ubiquitously expressed RNA-binding protein that stabilizes the mRNAs of certain
genes and regulates the translation to proteins. Elevated cytoplasmic expression of HuR has …

Defects in the adenosine-uridine (AU)-rich elements (AREs), which mediate post-
transcriptional regulation, play important roles in cancers. Both tristetraprolin (TTP, also …

miR-141 and miR-146b-5p are two important tumor suppressor microRNAs, which control
several cancer-related genes and processes. In the present report, we have shown that …