ABSTRACT H+ V-ATPases (V-ATPases) are found in two principal locations, in
endomembranes and in plasma membranes. The plasma membrane V-ATPase from the …

Abstract Vacuolar H+-ATPases (V-ATPases) are a family of ATP-driven proton pumps. They
maintain pH gradients between intracellular compartments and are required for proton …

In eukaryotic cells the interior space of endosomes, lysosomes, and a variety of other
intracellular organelles is maintained at a pH considerably more acidic than either cytosolic …

Vacuolar H+-ATPases (V-ATPases) are essential for acidification of intracellular
compartments and for proton secretion from the plasma membrane in kidney epithelial cells …

Metabolic traits of macrophages can be rewired by insulin-like growth factor 2 (IGF2);
however, how IGF2 modulates macrophage cellular dynamics and functionality remains …

Energy metabolism becomes dysregulated in individuals with obesity and many of these
changes persist after weight loss and likely play a role in weight regain. In these studies, we …

At present, liver ischemia‐reperfusion (IR) injury is still a great challenge for clinical liver
partial resection and liver transplantation. The innate immunity regulated by liver …

In vertebrates, TFEB (transcription factor EB) and MITF (microphthalmia-associated
transcription factor) family of basic Helix-Loop-Helix (bHLH) transcription factors regulates …

We have identified a cDNA encoding a novel isoform of the mouse V-ATPase d subunit (d2).
The protein encoded is 350 amino acids in length and shows 42 and 67% identity to the …

ABSTRACT Vacuolar-type ATPases (V-ATPases) are proton-translocating enzymes that
occur in the endomembranes of all eukaryotes and in the plasma membranes of many …