Electrophysiological and structural remodeling of the atria in a mouse model of troponin-I mutation linked hypertrophic cardiomyopathy: implications for atrial …

WW Lim, M Neo, S Thanigaimani, P Kuklik… - International Journal of …, 2021 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disorder affecting one in 500 of
the general population. Atrial fibrillation (AF) is the most common arrhythmia in patients with …

Kvβ1. 1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity

J Tur, KC Chapalamadugu, C Katnik… - American Journal …, 2017 - journals.physiology.org
The present study investigates the physiological role of Kvβ1 subunit for sensing pyridine
nucleotide (NADH/NAD+) changes in the heart. We used Kvβ1. 1 knockout (KO) or wild-type …

Atenolol reduces cardiac-mediated mortality in genetic mouse model of sudden unexpected death in epilepsy

MS Soh, A Kuanyshbek, ES Mohamed Syazwan… - bioRxiv, 2023 - biorxiv.org
Abstract Sudden Unexpected Death in Epilepsy (SUDEP) is the leading cause of premature
mortality in epilepsy. Genetic cardiac risk factors, including loss-of-function KCNH2 variants …

Association between heart rate variability indices and features of spontaneous ventricular tachyarrhythmias in mice

M He, WB Zhao, MN Nguyen, H Kiriazis… - Clinical and …, 2020 - Wiley Online Library
Direct evidence is limited for the association between heart rate variability (HRV) indices
and ventricular tachyarrhythmias (VTAs). While galectin‐3 (Gal‐3) is regarded as a causal …

[HTML][HTML] Kvβ1. 1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity

J Tur, KC Chapalamadugu, C Katnik… - American Journal of …, 2016 - pmc.ncbi.nlm.nih.gov
The present study investigates the physiological role of Kvβ1 subunit for sensing pyridine
nucleotide (NADH/NAD+) changes in the heart. We used Kvβ1. 1 knockout (KO) or wild-type …