Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study
Complications of the worldwide use of non-steroidal anti-inflammatory drugs (NSAIDs)
sparked scientists to design novel harmless alternatives as an urgent need. So, a unique …
sparked scientists to design novel harmless alternatives as an urgent need. So, a unique …
Synthesis, characterization, optical properties, biological activity and theoretical studies of a 4 nitrobenzylidene) amino) phenyl) imino) methyl) naphthalen-2-ol-based …
SM AlHazmy, MO Zouaghi, AN Al-Hakimi, T Alorini… - Heliyon, 2024 - cell.com
Abstract A new Schiff base, 1-(E)-(4-((E) 4nitrobenzylidene) amino) phenyl) imino) methyl)
naphthalen-2-ol (4NMN), was prepared from the reaction of p-phenylenediamine with 2 …
naphthalen-2-ol (4NMN), was prepared from the reaction of p-phenylenediamine with 2 …
Synthesis, optical properties, DNA, β-cyclodextrin interaction, hydrogen isotope sensor and computational study of new enantiopure isoxazolidine derivative (ISoXD)
A Alotayeq, S Ghannay, IA Alhagri, I Ahmed… - Heliyon, 2024 - cell.com
A novel isoxazolidine derivative (ISoXD) dye was successfully synthesized and
comprehensively characterized. In this study, we conducted a thorough examination of its …
comprehensively characterized. In this study, we conducted a thorough examination of its …
Biological determination, molecular docking and Hirshfeld surface analysis of rhoduim (I)-N-heterocyclic carbene complex: synthesis, crystal structure, DFT …
MO Zouaghi, N Amri, S Hassen, Y Arfaoui… - Inorganica Chimica …, 2023 - Elsevier
The synthesis and characterization of 1-(isobutyl)-3-(2.3. 5.6 tetramethylbenzyl)-5.6-
dimethylbenzimidazolium chloride and its N-functionalized Rhodium (I) N-heterocyclic …
dimethylbenzimidazolium chloride and its N-functionalized Rhodium (I) N-heterocyclic …
Prediction of Protein Allosteric Sites with Transfer Entropy and Spatial Neighbor-Based Evolutionary Information Learned by an Ensemble Model
F Hu, F Chang, L Tao, X Sun, L Liu… - Journal of Chemical …, 2024 - ACS Publications
Allostery is one of the most direct and efficient ways to regulate protein functions. The
diverse allosteric sites make it possible to design allosteric modulators of differential …
diverse allosteric sites make it possible to design allosteric modulators of differential …
Synthesis, optical properties, DNA, β-cyclodextrin interactions, and antioxidant evaluation of novel isoxazolidine derivative (ISoXD2): A multispectral and …
ISoXD2 are well explored among versatile and outstanding class of pharmacophores for the
preparation and discovery of drugs. Herein, the electronic absorption and emission spectra …
preparation and discovery of drugs. Herein, the electronic absorption and emission spectra …
Insights on Stability Constants and Structures of Complexes between Coumarin Derivatives and Pb (II) in Aqueous Media
In the frame of a systematic study on the sequestering ability of natural antioxidants towards
metal cations, here the complexation of coumarin-3-carboxilic acid (HCCA) with Pb (II) and …
metal cations, here the complexation of coumarin-3-carboxilic acid (HCCA) with Pb (II) and …
The Effect of the Saudi Haloxylon ammodendron Shrub on Silver Nanoparticles: Optimal Biosynthesis, Characterization, Removability of Mercury Ions, Antimicrobial …
AN Al-Hakimi, TM Alresheedi, RA Albarrak - Inorganics, 2023 - mdpi.com
This research provides a sustainable way to treat water by removing heavy metal hazards
(mercury ion) and biological pollutants (several strains of bacteria and fungi) through the eco …
(mercury ion) and biological pollutants (several strains of bacteria and fungi) through the eco …
Synthesis, Characterization, DNA, Fluorescence, Molecular Docking, and Antimicrobial Evaluation of Novel Pd (II) Complex Containing O, S Donor Schiff Base Ligand …
MS Al-Fakeh, M Alrasheedi, AEME Mohammed… - …, 2024 - search.ebscohost.com
Pd (II) with the Schiff base ligand 2-Hydroxy-3-Methoxy Benzaldehyde-Thiosemicarbazone
(HMBATSC)(L2) and 2-aminobenzothiazole (2-ABZ)(L1) was synthesized. The Schiff base …
(HMBATSC)(L2) and 2-aminobenzothiazole (2-ABZ)(L1) was synthesized. The Schiff base …
Crystal Structure and Hirshfeld Surface Analysis of 3-(pyrrolidine-1-carbonyl)-2H-Chromen-2-One
F Odame, T Madanhire, EC Hosten - Journal of Structural Chemistry, 2024 - Springer
The crystal X-ray structure of 3-(pyrrolidine-1-carbonyl)-2H-chromen-2-one (1) has been
presented. The compound crystallizes in the triclinic space group with two molecules in the …
presented. The compound crystallizes in the triclinic space group with two molecules in the …