Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …

Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

Cortical iron has been shown to be elevated in Alzheimer's disease (AD), but the impact of
the directly measured iron on the clinical syndrome has not been assessed. We investigated …

Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Alzheimer's disease (AD), the most common type of senile dementia, includes the complex
pathogenesis of abnormal deposition of amyloid beta-protein (Aβ), phosphorylated tau (p …

Beta amyloid is a protein fragment snipped from the amyloid precursor protein (APP).
Aggregation of these peptides into amyloid plaques is one of the hallmarks of Alzheimer's …

Among the changes that typify Alzheimer's disease (AD) are neuroinflammation and
microglial activation, amyloid deposition perhaps resulting from compromised microglial …

A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ)
fibrils in the brain. Nevertheless, the links between Aβ and AD pathology remain …

The neocortex of the human brain is the seat of higher brain function. Modern imaging
techniques, chief among them magnetic resonance imaging (MRI), allow non-invasive …

Altered metabolism of biometals in the brain is a key feature of Alzheimer's disease, and
biometal interactions with amyloid-β are linked to amyloid plaque formation. Iron-rich …