Kinase inhibitors of marine origin

SB Bharate, SD Sawant, PP Singh… - Chemical …, 2013 - ACS Publications
The ocean occupies three-fourths of the Earth's surface and hosts approximately 80% of all
living species. In fact, some areas of the sea such as coral reefs possess a biodiversity …

Reprogramming methods and cell culture platforms

B Valamehr, P Flynn, R Abujarour… - US Patent …, 2022 - Google Patents
pluripotency genes were necessary to maintain the ground state resulting in genome
modified human pluripotent stem cells (Hanna et al., 2010a), which are unsuitable for …

Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture

M Amit, J Itskovitz-Eldor - US Patent 10,214,722, 2019 - Google Patents
2013-03-19 Assigned to TECHNION RESEARCH & DEVELOPMENT FOUNDATION
LIMITED reassignment TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED …

Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs

B Valamehr, R Abujarour, P Flynn - US Patent 10,844,356, 2020 - Google Patents
The invention provides cell culture conditions for culturing stem cells, including feeder-free
conditions for generating and culturing human induced pluripotent stem cells (iPSCs). More …

Methods of generating lineage-specific cells from undifferentiated human pluripotent stem cells cultured in a single cell suspension culture

M Amit, J Itskovitz-Eldor - US Patent 10,597,635, 2020 - Google Patents
2017-02-09 Assigned to TECHNION RESEARCH & DEVELOPMENT FOUNDATION
LIMITED reassignment TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED …

Single cells pluripotent stem cells in a suspension culture

M Amit, J Itskovitz-Eldor - US Patent 11,193,108, 2021 - Google Patents
2020-01-29 Assigned to TECHNION RESEARCH & DEVELOPMENT FOUNDATION
LIMITED reassignment TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED …

Novel methods of genetic modification of human pluripotent stem cells

MV Camarasa - Recent Patents on Regenerative Medicine, 2015 - ingentaconnect.com
Genomic engineering has enormous potential along basic research, drug discovery and cell
therapeutics. Many existing methods for targeted gene knockout mutagenesis or integration …

Platform for the induction and maintenance of ground state pluripotency

B Valamehr, M Robinson, R Abujarour - US Patent 11,441,126, 2022 - Google Patents
US11441126B2 - Platform for the induction and maintenance of ground state pluripotency -
Google Patents US11441126B2 - Platform for the induction and maintenance of ground state …

Methods and culture media for culturing pluripotent stem cells

M Amit, J Itskovitz-Eldor - US Patent 11,959,098, 2024 - Google Patents
2021-01-15 Assigned to TECHNION RESEARCH & DEVELOPMENT FOUNDATION
LIMITED reassignment TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED …

Recent patents on Achondroplasia: latest research development

B Colligris, F Huete… - Recent Patents on …, 2013 - ingentaconnect.com
Achondroplasia (ACH) is the most common pathology of the group of disorders called
chondrodysplasias. It is resulting from a mutation in the Fibroblast Growth Factor Receptor …