Mechanisms of deep brain stimulation
TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
Mechanism of deep brain stimulation: inhibition, excitation, or disruption?
S Chiken, A Nambu - The neuroscientist, 2016 - journals.sagepub.com
Deep brain stimulation (DBS), applying high-frequency electrical stimulation to deep brain
structures, has now provided an effective therapeutic option for treatment of various …
structures, has now provided an effective therapeutic option for treatment of various …
Insights and opportunities for deep brain stimulation as a brain circuit intervention
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
Network perspectives on the mechanisms of deep brain stimulation
CC McIntyre, PJ Hahn - Neurobiology of disease, 2010 - Elsevier
Deep brain stimulation (DBS) is an established medical therapy for the treatment of
movement disorders and shows great promise for several other neurological disorders …
movement disorders and shows great promise for several other neurological disorders …
Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain
MP Kelly - Cellular signalling, 2018 - Elsevier
Deficits in brain function that are associated with aging and age-related diseases benefit
very little from currently available therapies, suggesting a better understanding of the …
very little from currently available therapies, suggesting a better understanding of the …
Deep brain stimulation mechanisms: the control of network activity via neurochemistry modulation
CC McIntyre, RW Anderson - Journal of Neurochemistry, 2016 - Wiley Online Library
Deep brain stimulation (DBS) has revolutionized the clinical care of late‐stage Parkinson's
disease and shows promise for improving the treatment of intractable neuropsychiatric …
disease and shows promise for improving the treatment of intractable neuropsychiatric …
Physiological and anatomical decomposition of subthalamic neurostimulation effects in essential tremor
Postural tremor is the leading symptom in essential tremor, but in some cases intention
tremor and limb ataxia emerge and can become highly disabling features. Deep brain …
tremor and limb ataxia emerge and can become highly disabling features. Deep brain …
Neural signatures of indirect pathway activity during subthalamic stimulation in Parkinson's disease
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) produces an
electrophysiological signature called evoked resonant neural activity (ERNA); a high …
electrophysiological signature called evoked resonant neural activity (ERNA); a high …
Deep brain stimulation and L-DOPA therapy: concepts of action and clinical applications in Parkinson's disease
L-DOPA is still the most effective pharmacological therapy for the treatment of motor
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …
Latest view on the mechanism of action of deep brain stimulation
How does deep brain stimulation (DBS) applied at high frequency (100 Hz and above, HFS)
in diverse points of cortico‐basal ganglia thalamo‐cortical loops alleviate symptoms of …
in diverse points of cortico‐basal ganglia thalamo‐cortical loops alleviate symptoms of …