BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury

Z Hu, X Yu, P Chen, K Jin, J Zhou, G Wang… - Molecular …, 2023 - journals.sagepub.com
Mechanical allodynia can be evoked by punctate pressure contact with the skin (punctate
mechanical allodynia) and dynamic contact stimulation induced by gentle touching of the …

Brain-Derived Neurotrophic Factor, Nociception, and Pain

A Merighi - Biomolecules, 2024 - mdpi.com
This article examines the involvement of the brain-derived neurotrophic factor (BDNF) in the
control of nociception and pain. BDNF, a neurotrophin known for its essential role in …

Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid …

P Chen, N Huang, B Pang, Z Ye, R Luo… - Phytotherapy …, 2023 - Wiley Online Library
Neuropathic pain (NeP) is a major health concern. Due to the complex pathological
mechanisms, management of NeP is challenging. Emodin, a natural anthraquinone …

Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging‐induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the …

M Zargani, R Ramirez-Campillo… - Pflügers Archiv-European …, 2023 - Springer
Aging is associated with muscle atrophy, and erosion and destruction of neuronal pathways
in the spinal cord. The study aim was to assess the effect of swimming training (Sw) and L …

[PDF][PDF] Study about Neuroplasticity and Spinal Cord Injury: Pathophysiology and Epidemiology

VB Freire, LC Souza, MHL Martinelli… - Current Practice in …, 2022 - researchgate.net
Neuroplasticity is a phenomenon present from the intrauterine period to old age, exhibiting
distinct characteristics during the course of life. Neuroplasticity can be understood in three …