Function and activation of NF-kappa B in the immune system.
PA Baeuerle, T Henkel - Annual review of immunology, 1994 - europepmc.org
NF-kappa B is a ubiquitous transcription factor. Nevertheless, its properties seem to be most
extensively exploited in cells of the immune system. Among these properties are NF-kappa …
extensively exploited in cells of the immune system. Among these properties are NF-kappa …
Acetaminophen-induced hepatotoxicity
LP James, PR Mayeux, JA Hinson - Drug metabolism and disposition, 2003 - ASPET
The analgesic acetaminophen causes a potentially fatal, hepatic centrilobular necrosis
when taken in overdose. The initial phases of toxicity were described in Dr. Gillette's …
when taken in overdose. The initial phases of toxicity were described in Dr. Gillette's …
[PDF][PDF] Superoxide dismutase and stress tolerance
84 BOWLER ET AL organism's defense mechanism and have consequently been the
subject of much research. In plants, the role of SOD during environmental adversity, has …
subject of much research. In plants, the role of SOD during environmental adversity, has …
Hydrogen peroxide‐and glutathione‐associated mechanisms of acclimatory stress tolerance and signalling
Plants adapt to environmental stresses through specific genetic responses. The molecular
mechanisms associated with signal transduction, leading to changes in gene expression …
mechanisms associated with signal transduction, leading to changes in gene expression …
lnterleukin-8 and related chemotactic cytokines—CXC and CC chemokines
M Baggiolini, B Dewald, B Moser - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on interleukin-8 (IL-8) and related chemotactic
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new …
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new …
An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes
N Browne, M Heelan, K Kavanagh - Virulence, 2013 - Taylor & Francis
The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …
to the innate immune system of mammals. As a result of these conserved features insects …
Tryptophan and the immune response
JR Moffett, MAA Namboodiri - Immunology and cell biology, 2003 - Wiley Online Library
The immune system continuously modulates the balance between responsiveness to
pathogens and tolerance to non‐harmful antigens. The mechanisms that mediate tolerance …
pathogens and tolerance to non‐harmful antigens. The mechanisms that mediate tolerance …
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3, 4, 5-trisphosphate in neutrophil responses
Phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) is rapidly produced upon exposure of
neutrophils to the chemoattractant N-formylmethionyl-leucylphenylalanine (fMLP), and has …
neutrophils to the chemoattractant N-formylmethionyl-leucylphenylalanine (fMLP), and has …
Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione
E Clementi, GC Brown, M Feelisch… - Proceedings of the …, 1998 - National Acad Sciences
Both reversible and irreversible inhibition of mitochondrial respiration have been reported
following the generation of nitric oxide (NO) by cells. Using J774 cells, we have studied the …
following the generation of nitric oxide (NO) by cells. Using J774 cells, we have studied the …
In vitro assessments of nanomaterial toxicity
CF Jones, DW Grainger - Advanced drug delivery reviews, 2009 - Elsevier
Nanotechnology has grown from a scientific interest to a major industry with both commodity
and specialty nanomaterial exposure to global populations and ecosystems. Sub-micron …
and specialty nanomaterial exposure to global populations and ecosystems. Sub-micron …