Setting the scene and generating evidence for malaria elimination in Southern Mozambique

P Aide, B Candrinho, B Galatas, K Munguambe… - Malaria journal, 2019 - Springer
Mozambique has historically been one of the countries with the highest malaria burden in
the world. Starting in the 1960s, malaria control efforts were intensified in the southern …

Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2004 - thelancet.com
Background Development of an effective malaria vaccine could greatly contribute to disease
control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …

Malaria, anemia, and malnutrition in African children—defining intervention priorities

S Ehrhardt, GD Burchard, C Mantel… - The Journal of …, 2006 - academic.oup.com
Background Malaria, anemia, and malnutrition contribute substantially to childhood
morbidity in sub-Saharan Africa, but their respective roles and interactions in conferring …

Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

JJ Aponte, P Aide, M Renom, I Mandomando, Q Bassat… - The Lancet, 2007 - thelancet.com
Background Malaria remains a leading global health problem that requires the improved
use of existing interventions and the accelerated development of new control methods. We …

Safety and immunogenicity of RTS, S/AS02D malaria vaccine in infants

S Abdulla, R Oberholzer, O Juma… - … England Journal of …, 2008 - Mass Medical Soc
Background The RTS, S/AS malaria vaccine is being developed for delivery through the
World Health Organization's Expanded Program on Immunization (EPI). We assessed the …

Profile: Manhiça health research centre (Manhiça HDSS)

C Sacoor, A Nhacolo, D Nhalungo… - International journal …, 2013 - academic.oup.com
Abstract The Manhiça Health Research Centre, established in 1996 in a rural area of
southern Mozambique, currently follows around 92 000 individuals living in approximately …

The epidemiology of severe malaria at Manhiça District Hospital, Mozambique: a retrospective analysis of 20 years of malaria admissions surveillance data

C Guinovart, B Sigaúque, Q Bassat… - The Lancet Global …, 2022 - thelancet.com
Background Most malaria burden estimates rely on modelling infection prevalence to case
incidence data, with insufficient attention having been paid to the changing clinical …

Accuracy of a rapid diagnostic test on the diagnosis of malaria infection and of malaria-attributable fever during low and high transmission season in Burkina Faso

Z Bisoffi, SB Sirima, J Menten, C Pattaro, A Angheben… - Malaria Journal, 2010 - Springer
Background Malaria management policies currently recommend that the treatment should
only be administered after laboratory confirmation. Where microscopy is not available, rapid …

Insights into long-lasting protection induced by RTS, S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

C Guinovart, JJ Aponte, J Sacarlal, P Aide, A Leach… - PLoS …, 2009 - journals.plos.org
Background The pre-erythrocytic malaria vaccine RTS, S/AS02A has shown to confer
protection against clinical malaria for at least 21 months in a trial in Mozambican children …

Design of a phase III multicenter trial to evaluate the efficacy of the RTS, S/AS01 malaria vaccine in children across diverse transmission settings in Africa

A Leach, J Vekemans, M Lievens, O Ofori-Anyinam… - Malaria journal, 2011 - Springer
Abstract Background GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative
are working in partnership to develop a malaria vaccine to protect infants and children living …