Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
The immunology of long COVID
DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …
A bivalent omicron-containing booster vaccine against Covid-19
S Chalkias, C Harper, K Vrbicky… - … England Journal of …, 2022 - Mass Medical Soc
Background The safety and immunogenicity of the bivalent omicron-containing mRNA-
1273.214 booster vaccine are not known. Methods In this ongoing, phase 2–3 study, we …
1273.214 booster vaccine are not known. Methods In this ongoing, phase 2–3 study, we …
Distinguishing features of Long COVID identified through immune profiling
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …
CoV-2 can result in the development of a post-acute infection syndrome known as long …
[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection
AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
Unexplained post-acute infection syndromes
SARS-CoV-2 is not unique in its ability to cause post-acute sequelae; certain acute
infections have long been associated with an unexplained chronic disability in a minority of …
infections have long been associated with an unexplained chronic disability in a minority of …
Pathophysiology and mechanism of long COVID: a comprehensive review
D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …
patients enduring persistent symptoms long after acute infection is a matter of concern. This …
The immunology and immunopathology of COVID-19
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …