Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous
hyper-reactivity to environmental triggers that are innocuous to normal, non-atopic …

Atopic dermatitis (AD) is a multifactorial, chronic inflammatory skin disorder in which genetic
mutations and cutaneous hyperreactivity to environmental stimuli play a causative role …

Despite the large amount of money spent on research into pollution of the indoor
environment, the problem remains complex with major gaps in our knowledge of the …

The examination of house dust mite extracts has indicated that over 30 different proteins can
induce IgE antibody in patients allergic to the house dust mite. There are however dominant …

Extracellular endogenous proteases, as well as exogenous proteases from mites and molds,
react with cell-surface receptors in the airways to generate leukocyte infiltration and to …

abstract The allergenic load of house dust mite allergy is largely constituted by a few
proteins with a hierarchical pattern of allergenicity. The serodominant specificities are the …

Endogenous proteolytic enzymes have been shown to be potential sources of airway
inflammation inducing proinflammatory cytokine release from respiratory epithelial cells; …

Atopic dermatitis, one of the most common skin disorders in young children, has a
prevalence of 10% to 20% in the first decade of life. It is a chronic illness that requires a …

▪ Abstract Many species of arthropods are the sources of potent allergens that sensitize and
induce IgE-mediated allergic reactions in humans. Most of these arthropod allergens are …

Background: Two predominant mite species, Dermatophagoides farinae and
Dermatophagoides pteronyssinus, are responsible for the immediate hypersensitivity …