Novel carbon skeletons activate human NicotinAMide Phosphoribosyl Transferase (NAMPT) enzyme in biochemical assay
KH Almeida, L Avalos-Irving, S Berardinelli… - PLoS …, 2023 - journals.plos.org
Nicotinamide adenine dinucleotide (NAD) is a central molecule in cellular metabolism that
has been implicated in human health, the aging process, and an array of human diseases …
has been implicated in human health, the aging process, and an array of human diseases …
Interaction of 2, 6, 7-trihydroxy-xanthene-3-ones with iron and copper, and biological effect of the most active derivative on breast cancer cells and erythrocytes
P Mladěnka, J Karlíčková, M Hrubša, E Veljović… - Applied Sciences, 2020 - mdpi.com
Metal chelators can be potentially employed in the treatment of various diseases, ranging
from metal overload to neoplastic conditions. Some xanthene derivatives were previously …
from metal overload to neoplastic conditions. Some xanthene derivatives were previously …
Modelling of antiproliferative activity measured in HeLa cervical cancer cells in a series of xanthene derivatives
Cancer remains one of the leading causes of death in humans, and new drug substances
are therefore being developed. Thus, the anti-cancer activity of xanthene derivatives has …
are therefore being developed. Thus, the anti-cancer activity of xanthene derivatives has …
Analysis of Antitumor Potential of Xanthene Compounds in Lymphoma Cells
Sažetak Antitumor activity of two newly and sixteen previously synthesized 9-arylsubstituted
2, 6, 7-trihydroxyxanthene-3-ones on diffuse large B-cell lymphoma cells were analyzed in …
2, 6, 7-trihydroxyxanthene-3-ones on diffuse large B-cell lymphoma cells were analyzed in …
Effects of newly synthesized xanthene-3-ones on Pseudomonas aeruginosa–Experimental study on rats
A Smajović, E Veljović, M Čelebičić - Veterinaria, 2023 - veterinaria.unsa.ba
The need for new drugs that will have an antimicrobial effect is increasing every day.
Xanthenes are cyclic, organic compounds of natural, semi-synthetic or synthetic origin …
Xanthenes are cyclic, organic compounds of natural, semi-synthetic or synthetic origin …
Toxicity testing of newly synthesized xanthene-3-ones after parenteral applications: an experimental study in rats (Rattus norvegicus)
A Smajović, M Katica, D Zavšnik, E Veljović… - Veterinaria, 2020 - veterinaria.unsa.ba
Xanthenes are organic compounds that can be of natural, semi-synthetic and synthetic
origin. Many studies indicate that xanthene and its derivatives have antibacterial, antifungal …
origin. Many studies indicate that xanthene and its derivatives have antibacterial, antifungal …
DNA Binding Affinity Assessment of Xanthene Compounds: In Vitro and In Silico Approach
Sažetak Xanthene derivatives are an important class of heterocyclic compounds with a wide
spectrum of pharmacological activities. In our previous investigations, we found the good …
spectrum of pharmacological activities. In our previous investigations, we found the good …
Quantitative structure–activity relationships of xanthen-3-one and xanthen-1, 8-dione derivatives and design of new compounds with enhanced antiproliferative activity …
Xanthene derivatives have become a group of molecules of great importance in discovering
of new anticancer drugs. Recent studies of our group performed on xanthen-3-one and …
of new anticancer drugs. Recent studies of our group performed on xanthen-3-one and …
Application of Xanten and its derivatives in human and veterinary medicine
A Smajović, M Katica, D Završnik… - Atatürk Üniversitesi …, 2019 - dergipark.org.tr
Xanthene derivatives represent cyclic, organic compounds that can be natural, semi-
synthetic and synthetic origin. These compounds become very interesting because of …
synthetic and synthetic origin. These compounds become very interesting because of …
Antimicrobial and Antiproliferative Activities and Enzyme Binding Affinity of Xanthen-3-one Derivatives
Sažetak Ten biologically active derivatives of 2, 6, 7-trihydroxyxanthen-3-one, previously
synthesized and characterised, were investigated for their in vitro antimicrobial and …
synthesized and characterised, were investigated for their in vitro antimicrobial and …