Chemometrics tools in QSAR/QSPR studies: A historical perspective

S Yousefinejad, B Hemmateenejad - Chemometrics and Intelligent …, 2015 - Elsevier
One of the most extended subfields of chemometrics, at least by considering the number of
publications and interested researchers, is QSAR/QSPR. During the time, various improved …

FAM72, glioblastoma multiforme (GBM) and beyond

NTT Ho, CS Rahane, S Pramanik, PS Kim, A Kutzner… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is a serious and aggressive cancer
disease that has not allowed scientists to rest for decades. In this review, we consider the …

Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl) amino]-2-oxoethyl derivatives

M Rafiq, Y Nazir, Z Ashraf, H Rafique… - Journal of enzyme …, 2019 - Taylor & Francis
The over expression of melanogenic enzymes like tyrosinase caused many
hyperpigmentaion disorders. The present work describes the synthesis of hydroxy …

[HTML][HTML] Screening and demulsification mechanism of fluorinated demulsifier based on molecular dynamics simulation

X Geng, C Li, L Zhang, H Guo, C Shan, X Jia, L Wei… - Molecules, 2022 - mdpi.com
In order to solve the problem of demulsification difficulties in Liaohe Oilfield, 24 kinds of
demulsifiers were screened by using the interface generation energy (IFE) module in the …

Revisiting fish toxicity of active pharmaceutical ingredients: Mechanistic insights from integrated ligand-/structure-based assessments on acetylcholinesterase

N Minovski, MT Saçan, EM Eminoğlu, SS Erdem… - Ecotoxicology and …, 2019 - Elsevier
The release of active pharmaceutical ingredients (APIs) into the environment is of great
concern for aquatic ecosystem as many of these chemicals are designed to exert biological …

Structural exploration of PPARγ modulators through pharmacophore mapping, fragment-based design, docking, and molecular dynamics simulation analyses

A Nandy, K Roy, A Saha - Medicinal Chemistry Research, 2017 - Springer
Peroxisome proliferator-activated gamma receptor is an attractive therapeutic target
involving various types of metabolic syndrome. Viewing the importance of peroxisome …

Virtual Libraries for Docking Methods: Guidelines for the Selection and the Preparation

A Sellami, M Réau, F Langenfeld, N Lagarde… - Molecular Docking for …, 2021 - Elsevier
Prior to any docking study, the virtual compounds database that will be screened must be
carefully selected and prepared. This compound collection, often referred to as the virtual …

[PDF][PDF] FAM72, Glioblastoma Multiforme (GBM) and Beyond. Cancers 2021, 13, 1025

NTT Ho, CS Rahane, S Pramanik, PS Kim, A Kutzner… - 2021 - academia.edu
Neural stem cells (NSCs) offer great potential for regenerative medicine due to their
excellent ability to differentiate into various specialized cell types of the brain. In the central …

OF QSAR/QSPR MODELS

K ROY, S KAR - api.taylorfrancis.com
Quantitative structure–activity/property relationship (QSAR/QSPR) models being used for the
prediction of activity/property of untested chemicals can be exploited for the prioritization …

[引用][C] Chemometrics applications and research: QSAR in medicinal chemistry

AG Mercader, PR Duchowicz, PM Sivakumar - 2016 - CRC press