Alzheimer's disease (AD) is the most common cause of dementia. The pathophysiology of
this disease is characterized by the accumulation of amyloid-β, leading to the formation of …

Although the cause (s) of Alzheimer's disease in the majority of cases remains elusive, it has
long been associated with hypertension. In animal models of the disease, hypertension has …

It is known that insulin-degrading-enzyme (IDE) plays a crucial role in the clearance of
Alzheimer's amyloid-β (Aβ). The cysteine-free IDE mutant (cf-E111Q-IDE) is catalytically …

Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

Alzheimer's disease (AD) is the most common neurodegenerative disease (ND) and the
leading cause of dementia. It is characterized by non-linear, genetic-driven …

Dementia is a syndrome in which there is deterioration in memory, behavior, and the ability
to perform everyday activities. Alzheimer's disease and vascular dementia are the most …

Abstract Serotonin or 5-hydroxytryptamine (5-HT) is primarily involved in the regulation of
learning and memory. Pathological changes in metabolism or functional imbalance of 5-HT …

Background: Two classes of medications are used to treat Alzheimer's disease (AD);
donepezil, galantamine, and rivastigmine are acetylcholinesterase inhibitors, and …

Los mecanismos de neuroplasticidad del organismo constituyen la base de disímiles
terapias que buscan potenciar tales efectos para alcanzar una relativa mejoría en gran …

Alzheimer disease (AD) is the most common form of dementia in humans. However, to date,
the cause of sporadic AD (SAD), which is the most frequent form, is still unknown. Although it …