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Acute lymphoblastic leukaemia occurs in both children and adults but its incidence peaks
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …

Acute lymphoblastic leukemia (ALL) is the commonest childhood tumor and remains a
leading cause of cancer death in the young. In the last decade, microarray and sequencing …

Relapsed acute lymphoblastic leukaemia (ALL) is a leading cause of death due to disease
in young people, but the biological determinants of treatment failure remain poorly …

The oncogenic mechanisms underlying acute lymphoblastic leukemia (ALL) in adolescents
and young adults (AYA; 15–39 years old) remain largely elusive,,. Here we have searched …

Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …

We report 2 novel, cryptic chromosomal abnormalities in precursor B-cell acute
lymphoblastic leukemia (BCP-ALL): a translocation, either t (X; 14)(p22; q32) or t (Y; …

For most children who relapse with acute lymphoblastic leukemia (ALL), the prognosis is
poor, and there is a need for novel therapies to improve outcome. We screened samples …

B-precursor acute lymphoblastic leukemia (B-ALL) is the most common childhood tumor and
the leading cause of cancer-related death in children and young adults. The majority of B …

Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic
subgroup of childhood B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). To date …