Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India

A Srivastava, A Bandopadhyay, D Das… - Frontiers in …, 2020 - frontiersin.org
Studies on host-pathogen interaction have identified human ACE2 as a host cell receptor
responsible for mediating infection by coronavirus (COVID-19). Subsequent studies have …

The genetic makings of South Asia

M Metspalu, M Mondal, G Chaubey - Current opinion in genetics & …, 2018 - Elsevier
South Asia is home for more than a billion people culturally structured into innumerable
groups practicing different levels of endogamy. Linguistically South Asia is broadly …

[HTML][HTML] Distinct genetic variation and heterogeneity of the Iranian population

Z Mehrjoo, Z Fattahi, M Beheshtian, M Mohseni… - PLoS …, 2019 - journals.plos.org
Iran, despite its size, geographic location and past cultural influence, has largely been a
blind spot for human population genetic studies. With only sparse genetic information on the …

Advancements and Challenges in Ancient DNA Research: Bridging the Global North–South Divide

V Dalal, N Pasupuleti, G Chaubey, N Rai, V Shinde - Genes, 2023 - mdpi.com
Ancient DNA (aDNA) research first began in 1984 and ever since has greatly expanded our
understanding of evolution and migration. Today, aDNA analysis is used to solve various …

[HTML][HTML] Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 case fatality rate among Indian populations

RK Pandey, A Srivastava, PP Singh… - Infection, Genetics and …, 2022 - Elsevier
Abstract SARS-CoV-2, the causative agent for COVID-19, an ongoing pandemic, engages
the ACE2 receptor to enter the host cell through S protein priming by a serine protease …

[HTML][HTML] The genetic ancestry of modern Indus valley populations from northwest India

AK Pathak, A Kadian, A Kushniarevich… - The American Journal of …, 2018 - cell.com
The Indus Valley has been the backdrop for several historic and prehistoric population
movements between South Asia and West Eurasia. However, the genetic structure of …

Pinpointing the geographic origin of 165-year-old human skeletal remains found in Punjab, India: evidence from mitochondrial DNA and stable isotope analysis

JS Sehrawat, S Agrawal, D Sankhyan, M Singh… - Frontiers in …, 2022 - frontiersin.org
In 2014, 157 years after the Sepoy Mutiny of 1857, several unidentified human skeletons
were discovered in an abandoned well at Ajnala, Punjab. The most prevailing hypothesis …

Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations

RK Pandey, A Srivastava, RK Mishra, PP Singh… - Scientific Reports, 2024 - nature.com
SARS CoV-2, the causative agent for the ongoing COVID-19 pandemic, it enters the host
cell by activating the ACE2 receptor with the help of two proteasesi. e., Furin and TMPRSS2 …

A comprehensive exploration of the genetic legacy and forensic features of Afghanistan and Pakistan Mongolian-descent Hazara

G He, A Adnan, A Rakha, HY Yeh, M Wang… - Forensic Science …, 2019 - Elsevier
Afghanistan and Pakistan are rich with a complex landscape of culture, linguistics, ethnicity
and genetic legacy at the crossroads between Indian-Subcontinent and Central Asia …

The major genetic risk factor for severe COVID-19 does not show any association among South Asian populations

PP Singh, A Srivastava, GNN Sultana, N Khanam… - Scientific Reports, 2021 - nature.com
With the growing evidence on the variable human susceptibility against COVID-19, it is
evident that some genetic loci modulate the severity of the infection. Recent studies have …