Electrochemical detection of metabolites is essential for early diagnosis and continuous
monitoring of a variety of health conditions. This review focuses on organic electronic …

Living organisms evolve complex genetic networks to interact with the environment. Due to
the rapid development of synthetic biology, various modularized genetic parts and units …

Rapidly growing yeasts with appropriate posttranslational modifications are favored hosts for
protein production in the biopharmaceutical industry. However, limited production capacity …

A variety of chemicals have been produced through metabolic engineering approaches, and
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …

Highlights•Genetically encoded biosensors are used in evolutionary metabolic
engineering.•These biosensors are constructed from natural or artificial genetic …

The catalytic null mutant of the Cas9 endonuclease from the bacterial CRISPR immune
system, known as dCas9, can be guided by a small RNA to bind DNA sequences of interest …

Gram-positive Staphylococcus aureus infection that results in pneumonia, urinary tract
infection, and in severe cases, sepsis, has recently been classified as a serious threat to …

Ribozymes are functional RNA molecules that can catalyze biochemical reactions. Since the
discovery of the first catalytic RNA, various functional ribozymes (eg, self-cleaving …

Riboswitches and toehold switches are considered to have potential for implementation in
various fields, ie, biosensing, metabolic engineering, and molecular diagnostics. The …

Non-coding RNAs (ncRNAs) are versatile and powerful controllers of gene expression that
have been increasingly linked to cellular metabolism and phenotype. In bacteria, identified …