Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …

Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …

Metabolic syndrome is a common metabolic disorder which has become a public health
challenge worldwide. There has been growing interest in medications including natural …

Silymarin, which is extracted from the milk thistle (Silybum marianum), has been used for
centuries for treating hepatic disorders and its hepatoprotective effects have been known for …

Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common
products widely used in the phytotherapy of liver diseases. They also have promising effects …

Silymarin, a flavonolignan from the seeds of'milk thistle'(Silybum marianum (L.) Gaertn.)),
has been widely used from ancient times because of its excellent hepato-protective action. It …

Extracts of milk thistle (Silybum marianum, Asteraceae) have been recognized for centuries
as remedies for liver and gallbladder disorders. The active constituents of milk thistle fruits …

This review focuses on the specific biological effects of optically pure silymarin flavo-
nolignans, mainly silybins A and B, isosilybins A and B, silychristins A and B, and their 2, 3 …

Metabolic syndrome is a collection of abnormalities including insulin resistance,
hypertension, dyslipidemia, type 2 diabetes, obesity, inflammation, non-alcoholic fatty liver …

This study evaluated the absorption and metabolism of milk thistle flavonolignans
silychristin, silydianin, silybin and isosilybin isomers (all together known as silymarin) in …