Astrocyte regulation of neural circuit activity and network states

JF Oliveira, A Araque - Glia, 2022 - Wiley Online Library
Astrocytes are known to influence neuronal activity through different mechanisms, including
the homeostatic control of extracellular levels of ions and neurotransmitters and the …

[HTML][HTML] Astrocytes in selective vulnerability to neurodegenerative disease

TS Zimmer, AL Orr, AG Orr - Trends in neurosciences, 2024 - cell.com
Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

[HTML][HTML] Adenosine-independent regulation of the sleep–wake cycle by astrocyte activity

W Peng, X Liu, G Ma, Z Wu, Z Wang, X Fei, M Qin… - Cell discovery, 2023 - nature.com
Astrocytes play a crucial role in regulating sleep–wake behavior, and adenosine signaling is
generally thought to be involved. Here we show multiple lines of evidence supporting that …

[HTML][HTML] Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice

F Wang, W Wang, S Gu, D Qi, NA Smith… - Nature …, 2023 - nature.com
Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to
the modulation of sensory transmission during different brain states remains largely …

[HTML][HTML] The stress of losing sleep: Sex-specific neurobiological outcomes

CJ Wright, S Milosavljevic, A Pocivavsek - Neurobiology of stress, 2023 - Elsevier
Sleep is a vital and evolutionarily conserved process, critical to daily functioning and
homeostatic balance. Losing sleep is inherently stressful and leads to numerous detrimental …

[HTML][HTML] Astrocytes: integrators of arousal state and sensory context

RN Rasmussen, A Asiminas, EMM Carlsen… - Trends in …, 2023 - cell.com
The integration of external information with the internal state of the body is central to the
survival of virtually every multicellular organism. However, a complete picture of the …

Goodnight, astrocyte: waking up to astroglial mechanisms in sleep

AM Ingiosi, MG Frank - The FEBS journal, 2023 - Wiley Online Library
Astrocytes mediate many important aspects of neural homeostasis, but until recently, their
role in sleep was largely unknown. The situation has dramatically changed in the last …

[HTML][HTML] Engram reactivation mimics cellular signatures of fear

RL Suthard, RA Senne, MD Buzharsky, AH Diep… - Cell Reports, 2024 - cell.com
Engrams, or the physical substrate of memory, recruit heterogeneous cell types. Targeted
reactivation of neurons processing discrete memories drives the behavioral expression of …

[HTML][HTML] Circadian mechanisms in brain fluid biology

VS Vizcarra, RM Fame, LM Hablitz - Circulation Research, 2024 - Am Heart Assoc
The brain is a complex organ, fundamentally changing across the day to perform basic
functions like sleep, thought, and regulating whole-body physiology. This requires a …

Control of complex behavior by astrocytes and microglia

PI Ortinski, KJ Reissner, J Turner, TL Anderson… - Neuroscience & …, 2022 - Elsevier
Evidence that glial cells influence behavior has been gaining a steady foothold in scientific
literature. Out of the five main subtypes of glial cells in the brain, astrocytes and microglia …