Differentiation of the Drosophila compound eye from the eye imaginal disc is a progressive
process: columns of cells successively differentiate in a posterior to anterior sequence …

Sensory placodes are unique columnar epithelia with neurogenic potential that develop in
the vertebrate head ectoderm next to the neural tube. They contribute to the paired sensory …

Specialized cellular microenvironments, or 'niches', modulate stem cell properties, including
cell number, self-renewal and fate decisions,. In the adult brain, niches that maintain a …

The precise coordination of signals that control proliferation is a key feature of growth
regulation in developing tissues [1]. While much has been learned about the basic …

Cranial placodes are focal regions of columnar epithelium next to the neural tube that
contribute to sensory ganglia and organs in the vertebrate head, including the olfactory …

The Drosophila eye is a highly ordered epithelial tissue composed of∼ 750 subunits called
ommatidia arranged in a reiterated hexagonal pattern. At higher resolution, observation of …

Metazoan development relies on a highly regulated network of interactions between
conserved signal transduction pathways to coordinate all aspects of cell fate specification …

The Bmp family of secreted signaling molecules is implicated in multiple aspects of
embryonic development. However, the cell-type-specific requirements for this signaling …

Cell cycle investigations have focused on relentless exponential proliferation of cells, an
unsustainable situation in nature. Proliferation of cells, whether microbial or metazoan, is …

The compound eye of the fruit fly, Drosophila melanogaster, has for decades been used
extensively to study a number of critical developmental processes including tissue …