Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

Highly enantioselective biomimetic Michael addition reactions of malonic acid half thioesters
(MAHTs) to a variety of nitroolefins, affording the optically active γ‐amino acid precursors …

Different malonates and β‐ketoesters can react with N‐tert‐butoxycarbonyl‐(N‐Boc) and N‐
benzyloxycarbonyl‐(N‐Cbz) protected α‐amido sulfones in an organocatalytic asymmetric …

Direct catalytic asymmetric Mannich-type reaction of a trichloromethyl ketone as a
propionate equivalent donor is described. A new lanthanum aryloxide− i Pr-pybox+ lithium …

Abstract Design and applications of multimetallic bifunctional asymmetric catalysts based on
the proximity-effect-control concept are described. Suitable design of chiral ligands and …

Catalytic carbon–carbon bond‐forming reactions of weakly acidic carbon pronucleophiles
with N‐aryl imines, α, β‐unsaturated amides, and others under proton‐transfer conditions …

In the presence of catalytic amounts of potassium hexamethyldisilazide (KHMDS) and a
chiral macrocyclic crown ether, asymmetric 1, 4-addition reactions of simple esters with α, β …

Barium-catalyzed direct Mannich-type reactions of a β, γ-unsaturated ester are described.
The Ba-catalyst not only promoted the Mannich-type reactions, but also isomerized Mannich …