Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract that
leads to substantial suffering for millions of patients. In some patients, the chronic …

Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …

Background and Aims Intestinal strictures are a common complication of Crohn's disease
(CD). Biomarkers of intestinal strictures would assist in their prediction, diagnosis, and …

Inflammatory bowel disease (IBD), a general term encompassing Crohn's disease (CD) and
ulcerative colitis (UC), and other conditions, is a chronic and relapsing autoimmune disease …

Cholesterol is an essential structural component of all membranes of mammalian cells
where it plays a fundamental role not only in cellular architecture, but also, for example, in …

The gene encoding for Epstein-Barr virus-induced G-protein-coupled receptor 2 (EBI2) is a
risk gene for inflammatory bowel disease (IBD). Together with its oxysterol ligand 7α, 25 …

Immune cell trafficking is an important mechanism for the pathogenesis of inflammatory
bowel disease (IBD). The oxysterol receptor GPR183 and its ligands, dihydroxylated …

Cholesterol is a member of the sterol family that plays essential roles in biological
processes, including cell membrane stability and myelin formation. Cholesterol can be …

Inflammatory bowel diseases (IBDs), such as Crohn's disease and ulcerative colitis, are
lifelong diseases that remain challenging to treat. IBDs are characterized by alterations in …

Inflammation is a critical component of many lung diseases including asthma and acute lung
injury (ALI). Using high‐performance liquid chromatography–mass spectrometry, we …